DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9649 and T22A3.6

DIOPT Version :9

Sequence 1:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_492773.3	Gene:	T22A3.6 / 188711	WormBaseID:	WBGene00011909	Length:	491	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	80/417 - (19%)
Similarity:	123/417 - (29%)	Gaps:	150/417 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 WPQAPQTNYTVYEEEEEEEPVQRRRPQQRPSRPR-PQQAPSRPRLQPVPQLPQEPEFQTSARPSV 222
            |...|.:.:.:.:.......:.|..|.:..:..| |.:.|..|... |......|.|| ..|||.
Worm   114 WSSIPNSTFDISDSSSSSYSMNRILPDEYENFCRNPDKNPLGPWCY-VGNDTTAPCFQ-PCRPST 176

  Fly   223 HPSNTPAQASKF-------YPQTIGQLSGICGREKVI--------------QTPFIHNGIE---- 262
            ..|      |.|       :|.|...:|.|....::|              ..|.:.:|::
Worm   177 ETS------SDFVCLNRDGFPYTDYDMSDILDLPQLIGIFKDVDLMYESRFVLPSLPDGVQRLST 235

  Fly   263 ---VERGQL-----PWMAALFEHV--------GRDYNFLC-------------GGTLISA----R 294
               :.:|.:     ||:|.|.:..        .|....||             .|.|:.|    .
Worm   236 KSCINKGHIANHFGPWIAVLDQTATQFLAAAGRRKLRDLCFPSFNEHEIFTYQQGILLDAIIEDE 300

  Fly   295 TVISAA----HCFR-----------------FGSR--NLPGER-------TIVSLGRNSLDLFSS 329
            ..||..    .||.                 |||:  ::.|::       |...|....::..||
Worm   301 LTISGCTFWRRCFSSCQDDLATCWLKSQKGYFGSKATSVSGKQCIPWTQATSEILSMVKVNSTSS 365

  Fly   330 GATLGVARLLIHEQYNPNVY---------TDADLALLQLSNHVDI-GDYIKPICLWNENFLLELP 384
            |......|||..:   |:.:         |:|...||...|.|:: ..|.:.....||..:.|.
Worm   366 GVYHMYHRLLFED---PSQFFTESRLFMNTEASCMLLNRRNSVEVKNSYKESPFFTNEKLVSEF- 426

  Fly   385 SGHKSYVAGWGEDEKGNRNTRLAKMTDTDIITQWECRGNLSEENAKFITS--------HTICASN 441
              .|.:..|.|...|.|:.           |....|......|....:|.        ::||...
Worm   427 --EKLFQQGPGCFVKQNKT-----------IEFQSCYTECESEKKPTLTKPLCFEKNRYSICKPK 478

  Fly   442 AQASGPCSGDSGGGLMLQEQDIWMLRG 468
            .      |||            |:.||
Worm   479 R------SGD------------WLKRG 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	56/297 (19%)
		Tryp_SPc	259..497	CDD:214473	56/295 (19%)
T22A3.6	NP_492773.3	KR	98..173	CDD:350900	12/60 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100