DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9649 and try-5

DIOPT Version :9

Sequence 1:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_505421.3	Gene:	try-5 / 187088	WormBaseID:	WBGene00006623	Length:	327	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	78/301 - (25%)
Similarity:	123/301 - (40%)	Gaps:	51/301 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 ICGREKVIQTPFIHNGIEVERGQ----LPWMAALFEHVGR-DYNFLCGGTLISARTVISAAHCFR 304
            :|||:.. .|.|:........|.    .||...:.....: |:..:||||||:.:.|::|||||:
Worm    28 LCGRQST-YTSFMLTDAAGNTGNPTHLAPWAVQIRVKARKGDFEVICGGTLITLKHVLTAAHCFQ 91

  Fly   305 --FGSRNLPGE----------------------RTIVSLGR---------NSLDLFSSGATLGVA 336
              ||::...||                      ||:|::|.         ..::...:|.||.::
Worm    92 KHFGAKKEGGEENSMSGRYCESNQRFTDSEILTRTVVTVGAMCTRLEQKYGCVNEKQNGKTLKIS 156

  Fly   337 RLLIHEQYNPNVYTDADLALLQLSNHVDIGDYIKPICLWNENFLLE--LPSGHKSYVAGWGEDE- 398
            |..|.:.|..:.....|:.:|:|.:.:|..:.....||   .||.|  :.||......|||.|.
Worm   157 RFAIGDFYKTHCEQGNDIVILELESTIDDVEGANYACL---PFLPEVNIQSGANVTSFGWGSDPG 218

  Fly   399 KGNRNTRLAKMTDTDIITQWECRGNLSEENAKFITSHTICASNAQASGPCSGDSGGGLMLQEQDI 463
            ||..|.....:....:.|  |......|.....|...:.|.:..:....|||||||||...:.|.
Worm   219 KGFDNAAFPMIQVLTLAT--ETLATCEENWGTSIPFDSFCTAEEEDKNVCSGDSGGGLTFHQSDS 281

  Fly   464 --WMLRGVVSAGQRMTNRCNLTLP--VIYTDVAKHIEWLLS 500
              ..:..:||.|.........:.|  .|.|||.||.:::::
Worm   282 AREFIIAIVSYGSDCVQLIGGSEPRSQINTDVRKHQKFIVN 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	73/285 (26%)
		Tryp_SPc	259..497	CDD:214473	73/282 (26%)
try-5	NP_505421.3	Tryp_SPc	48..296	CDD:389826	66/252 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I3868
Isobase	1	0.950	-	0	Normalized mean entropy	S12259
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_124240
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910