DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dop1R1 and LOC567498

DIOPT Version :9

Sequence 1:	NP_001262563.1	Gene:	Dop1R1 / 41726	FlyBaseID:	FBgn0011582	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_005159907.1	Gene:	LOC567498 / 567498	-ID:	-	Length:	398	Species:	Danio rerio

Alignment Length:	409	Identity:	149/409 - (36%)
Similarity:	213/409 - (52%)	Gaps:	74/409 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 VVVGIFLSVLIFLSVAGNILVCLAIYTERSLR-RIGNLFLASLAIADLFVASLVMTFAGVNDLLG 192
            |.:|..||:|:..::.||.:||.|:...|.|| ::.|:|:.|||::||.||.|||.:....::.|
Zfish    22 VFLGCALSLLVLWTLLGNFMVCAAVLRFRHLRGKVTNVFIVSLAMSDLLVAVLVMPWKAATEVTG 86

  Fly   193 YWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAA 257
            :|.||: ||:.|||||:|||||||||||.||:|||..|.||.:|.|.:.||||::.::..|:::.
Zfish    87 HWAFGS-FCECWVAFDIMCSTASILNLCVISLDRYWAISDPFQYERKMNRRVALVMVSVTWIVSV 150

  Fly   258 FVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYA 322
            .:||||:.|..||.|...:...|......|...|:.:||:.||.||||.|..||:..|.|:|..|
Zfish   151 AISFVPVQLNWHRADLDTVNTSNWTTKEMCDSSLSRSYAISSSLISFYIPVAVMLVTYTRIYRIA 215

  Fly   323 QKHVKSIKAVTRPGEVAEK---------QRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAV 378
            |..:|||.::.|..|.|:.         .::::||    :.|.||
Zfish   216 QIQIKSISSLERAAERAQSCSAGARTCPLQHRAIR----ETKLFK-------------------- 256

  Fly   379 TVGVIMGVFLICWVPFFCVNITAAFC--KTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDA 441
            |:.||||||:.||.|||.:|....||  ..|:...||.:..|.|:.||:.|||||: ||.:||||
Zfish   257 TLSVIMGVFVCCWFPFFVLNCAVPFCHKPDCVSEATFNVFVWFGWCNSSLNPIIYA-FNSDFRDA 320

  Fly   442 FKRILTMRNPWCCAQDVGNIHPRNSDRFITDYAAKNVVVMNSGRSSAELEQVSAIXPKCCLNLTG 506
            |.|:|..|. .|....||             ...|:.|.:|:                     .|
Zfish   321 FARLLCCRG-LCSKTPVG-------------VQCKDPVAINN---------------------QG 350

  Fly   507 GGATWLPCGCGGL-RVDDD 524
            ...|.:..||... |:|::
Zfish   351 SSVTTMEVGCASFSRMDNE 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	64/132 (48%)
Dop1R1	NP_001262563.1	7tm_1	145..431	CDD:278431	120/297 (40%)
LOC567498	XP_005159907.1	7tm_1	38..311	CDD:278431	120/297 (40%)
LOC567498	XP_005159907.1	7tm_4	<104..>156	CDD:304433	27/51 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	234	1.000	Domainoid score	I2313
eggNOG	1	0.900	-	-		E33208_3B9BF
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3173
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1045889at2759
OrthoFinder	1	1.000	-	-		FOG0001416
OrthoInspector	1	1.000	-	-		otm24276
orthoMCL	1	0.900	-	-		OOG6_107579
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4063
SonicParanoid	1	1.000	-	-		X883
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.760