Protein Alignment Dop1R1 and htr1d

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001139158.1
• Gene: htr1d / 556429
• ZFINID: ZDB-GENE-090409-3
• Length: 386
• Species: Danio rerio
• Alignment Length: 396
• Identity: 107/396 - (27%)
• Similarity: 172/396 - (43%)
• Gaps: 73/396 - (18%)

  Fly    95 TTLTSFYNESSWTNASEMDTIVGEEPEPLSLVSI-VVVGIFLSVLIFLSVAGNILVCLAIYTERS 158
            |||      .||.:|              :|:|: :.:...|:::...:...|..|...|:..|.
Zfish    20 TTL------ESWDDA--------------TLLSLQISISAMLAIVTLATALSNAFVIATIFLTRK 64

  Fly   159 LRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAIS 223
            |....|..:.|||..||.|:.|||..:.|..:...|..|...||.|::.|:...|||||:||.|:
Zfish    65 LHTPANFLIGSLAATDLLVSILVMPISIVYTVSKTWTLGQIVCDIWLSSDITFCTASILHLCVIA 129

  Fly   224 MDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKY---P 285
            :|||..|.|.|.|.:..|.|.|.:.|..:|:::..:|..|            :|....|.:   .
Zfish   130 LDRYWAITDALEYSKRRTMRRAALMIVIVWVISVSISLPP------------LFWRQAKAHEELT 182

  Fly   286 TCALDLTP-TYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEK-------Q 342
            .|.::... :|.:.|:..:||.|.|:::.:|.|:|..|:..:....|.:.....|.:       .
Zfish   183 ECMVNTDQISYTLYSTFGAFYVPTVLLMILYGRIYVAARSRIFKTPATSGKRFTAAQLIQNSAGS 247

  Fly   343 RYKSIRRPKNQPKKFKVRN---------------LHTHSSPYHVSD-------------HKAAVT 379
            ...|:....||........               |.|:|....::|             .||..|
Zfish   248 SLCSLNSTSNQEGHLNAGGGGGSGGGGGGGGGSPLFTNSVKVKLADSVLERKRLCAAREKKATKT 312

  Fly   380 VGVIMGVFLICWVPFFCVNITAAFCKTC-IGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFK 443
            :|:|:|.|::||:|||...:....||.| .....|.:.|||||.||..||:||:.||.:|:.||.
Zfish   313 LGIILGAFIVCWLPFFVFTLVMGVCKDCWYHPVLFDVFTWLGYLNSLINPVIYTAFNDDFKQAFH 377

  Fly   444 RILTMR 449
            :::..:
Zfish   378 KLIKFK 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	97/351 (28%)
		TM helix 1	130..156	CDD:320193	4/25 (16%)
		TM helix 2	163..189	CDD:320193	11/25 (44%)
		TM helix 3	201..231	CDD:320193	15/29 (52%)
		TM helix 4	243..265	CDD:320193	6/21 (29%)
		TM helix 5	292..321	CDD:320193	9/29 (31%)
		TM helix 6	371..401	CDD:320193	13/42 (31%)
		TM helix 7	410..435	CDD:320193	12/24 (50%)
htr1d	NP_001139158.1	7tmA_5-HT1B_1D	31..376	CDD:320455	98/356 (28%)
		TM helix 1	36..62	CDD:320455	4/25 (16%)
		TM helix 2	69..95	CDD:320455	11/25 (44%)
		TM helix 3	107..137	CDD:320455	15/29 (52%)
		TM helix 4	149..172	CDD:320455	6/34 (18%)
		TM helix 5	190..219	CDD:320455	9/28 (32%)
		TM helix 6	304..334	CDD:320455	12/29 (41%)
		TM helix 7	344..369	CDD:320455	12/24 (50%)