Protein Alignment Dop1R1 and Taar9

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001010831.1
• Gene: Taar9 / 503558
• MGIID: 3527454
• Length: 348
• Species: Mus musculus
• Alignment Length: 383
• Identity: 105/383 - (27%)
• Similarity: 159/383 - (41%)
• Gaps: 72/383 - (18%)

  Fly    78 DLDIEIDIQLLTNGYDGTTLTSFYNESSWTNASEMDTIVGEEPEPLSLVSIVVVGIFLSVLIFLS 142
            |...|..::|.....:|:.:.|.|  :.|..|                   ::.|: |.:...|:
Mouse     4 DFSPEPPMELCYENVNGSCIKSSY--APWPRA-------------------ILYGV-LGLGALLA 46

  Fly   143 VAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAF 207
            |.||:||.:||...:.|....|..:||||.||..|...||.|:.|..:...|.||..:|.....|
Mouse    47 VFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCF 111

  Fly   208 DVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPD 272
            |.....||:.:||.||:||||.:.|||.|....|..|:.:.||..|..:...||.....|.:
Mouse   112 DTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGAN--- 173

  Fly   273 QPLIFEDNGKKYPTCALDLTPTYAVVSSC-------------ISFYFPCVVMIGIYCRLYCYAQK 324
                  :.|.:      :|......|..|             :.|:.|.|||:.:|.|::..|:.
Mouse   174 ------EEGIE------ELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKY 226

  Fly   325 HVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLI 389
            ..:.|:......: |..:.||. |..|.                    :.|||.|:|:.|..||:
Mouse   227 QARKIEGTANQAQ-ASSESYKE-RVAKR--------------------ERKAAKTLGIAMAAFLV 269

  Fly   390 CWVPFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILT 447
            .|:|:....:..|:.........::||.|..|.|||.||:||:.|...||.|.|.|::
Mouse   270 SWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	94/324 (29%)
		TM helix 1	130..156	CDD:320193	10/25 (40%)
		TM helix 2	163..189	CDD:320193	12/25 (48%)
		TM helix 3	201..231	CDD:320193	13/29 (45%)
		TM helix 4	243..265	CDD:320193	6/21 (29%)
		TM helix 5	292..321	CDD:320193	9/41 (22%)
		TM helix 6	371..401	CDD:320193	10/29 (34%)
		TM helix 7	410..435	CDD:320193	11/24 (46%)
Taar9	NP_001010831.1	7tmA_TAAR6_8_9	34..322	CDD:320439	94/325 (29%)
		TM helix 1	34..60	CDD:320439	10/26 (38%)
		TM helix 2	67..93	CDD:320439	12/25 (48%)
		TM helix 3	105..135	CDD:320439	13/29 (45%)
		TM helix 4	147..170	CDD:320439	6/22 (27%)
		Extracellular Loop 2 (ECL2). /evidence=ECO:0000269|PubMed:37225986	174..187		2/18 (11%)
		TM helix 5	194..223	CDD:320439	7/28 (25%)
		TM helix 6	251..281	CDD:320439	11/49 (22%)
		TM helix 7	290..315	CDD:320439	11/24 (46%)