Protein Alignment Dop1R1 and Taar3

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001008429.1
• Gene: Taar3 / 493809
• MGIID: 3527427
• Length: 343
• Species: Mus musculus
• Alignment Length: 352
• Identity: 94/352 - (26%)
• Similarity: 161/352 - (45%)
• Gaps: 62/352 - (17%)

  Fly   129 VVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGY 193
            :::.:|::..:.:::.||:::.::|...:.|....|..:.|:|..|..:..::|.::.|..:...
Mouse    32 MIMYLFMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESC 96

  Fly   194 WIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAF 258
            |.||..||....:||:|.|..||.:||:|::||:..:.|||.|...:|..:....:|..|...|.
Mouse    97 WYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCDPLHYTTTMTVSMIKRLLAFCWAAPAL 161

  Fly   259 VSFVPISLGIHRPDQPLIFEDN--GKK--------YPTCALDLTPTYAVVSSCISFYFPCVVMIG 313
            .||     |:      ::.|.|  |.:        :..|||.....:..:.....|:.|..:|:|
Mouse   162 FSF-----GL------VLSEANVSGMQSYEILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVG 215

  Fly   314 IYCRLYCYAQKHVKSIK---AVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHK 375
            ||.:::..:::|.:::.   |.|: |.|.           ||..||               .|.|
Mouse   216 IYGKIFIVSRRHARALSDMPANTK-GAVG-----------KNLSKK---------------KDRK 253

  Fly   376 AAVTVGVIMGVFLICWVPFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRD 440
            ||.|:|::|||||.||:|.|...:...:...........:|.||||.||..||:|:..|...||.
Mouse   254 AAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRK 318

  Fly   441 AFKRILTMRNPWCCAQDVGNIHPRNSD 467
            |.:.|::           |.|...|||
Mouse   319 ALQFIVS-----------GKIFRSNSD 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	87/324 (27%)
		TM helix 1	130..156	CDD:320193	4/25 (16%)
		TM helix 2	163..189	CDD:320193	6/25 (24%)
		TM helix 3	201..231	CDD:320193	12/29 (41%)
		TM helix 4	243..265	CDD:320193	5/21 (24%)
		TM helix 5	292..321	CDD:320193	6/28 (21%)
		TM helix 6	371..401	CDD:320193	15/29 (52%)
		TM helix 7	410..435	CDD:320193	10/24 (42%)
Taar3	NP_001008429.1	7tmA_TAAR2_3_4	32..320	CDD:320437	87/325 (27%)
		TM helix 1	33..59	CDD:320437	4/25 (16%)
		TM helix 2	66..92	CDD:320437	6/25 (24%)
		TM helix 3	104..134	CDD:320437	12/29 (41%)
		TM helix 4	146..169	CDD:320437	6/33 (18%)
		Extracellular Loop 2 (ECL2). /evidence=ECO:0000250|UniProtKB:Q5QD04	173..186		1/12 (8%)
		TM helix 5	194..223	CDD:320437	6/28 (21%)
		TM helix 6	249..279	CDD:320437	16/44 (36%)
		TM helix 7	288..313	CDD:320437	10/24 (42%)