Protein Alignment Dop1R1 and 5-HT2B

DIOPT Version :9

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001262373.1
• Gene: 5-HT2B / 41017
• FlyBaseID: FBgn0261929
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 112/351 - (31%)
• Similarity: 169/351 - (48%)
• Gaps: 69/351 - (19%)

  Fly    44 TIGGNHTSGSTGFSTNSTLLDADHLPLQLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNE---SS 105
            ::|..:.||...:|::..|:..:....|.|||..                    ||.:|:   :.
  Fly     8 SLGAYNDSGGDDWSSSEHLVLWEEDETQRTTANA--------------------TSRHNQLHVAR 52

  Fly   106 WTNASEMDTIVGE-EPEPL------SLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIG 163
            | ||:...||... |..|.      :|:::        ||:..:.||||||||||..||.|:.:.
  Fly    53 W-NATGNATISATFEDVPFDANNYWALLAL--------VLVLGTAAGNILVCLAIAWERRLQNVT 108

  Fly   164 NLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYI 228
            |.||.||||.||.||.|||....:..:.||:..|::.|.||:..||:..||||::||.||:|||:
  Fly   109 NYFLMSLAITDLMVAVLVMPLGILTLVKGYFPLGSEHCLTWICLDVLFCTASIMHLCTISVDRYL 173

  Fly   229 HIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTP 293
            .::.|:|:||..|||...:.|..:|||:..:| :|:||...:....::.  ||    ||.:. .|
  Fly   174 SLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMS-LPLSLMYSKNHASVLV--NG----TCQIP-DP 230

  Fly   294 TYAVVSSCISFYFPCVVMIGIYC---RLYCYAQKHVKSIK--AVTRP-------GEVAEKQRYKS 346
            .|.:|.|.:.||.|..||:..||   ||....::::...:  |...|       |:....:|..:
  Fly   231 VYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCT 295

  Fly   347 IRR-----PKNQPKKFKVRNLHTHSS 367
            .||     |.|....     ||.||:
  Fly   296 WRRLLKPGPGNASSV-----LHAHSA 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	61/131 (47%)
		7tm_1	145..431	CDD:278431	89/240 (37%)
5-HT2B	NP_001262373.1	7tm_1	90..>262	CDD:278431	77/179 (43%)
		7tm_4	90..>238	CDD:304433	67/155 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940