Protein Alignment Dop1R1 and 5-HT2A

DIOPT Version :9

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_730859.1
• Gene: 5-HT2A / 40575
• FlyBaseID: FBgn0087012
• Length: 930
• Species: Drosophila melanogaster
• Alignment Length: 676
• Identity: 142/676 - (21%)
• Similarity: 209/676 - (30%)
• Gaps: 302/676 - (44%)

  Fly    47 GNHTSGSTGFSTNSTLLDADHLPL---QLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNESSWTN 108
            |....|...|...|.|::.||..|   .:|...:|:       .|.|      ||:. |.:|..:
  Fly   213 GAERDGLWSFLNLSELMEPDHGFLGIMNVTNTSLDM-------FLPN------LTAL-NTTSTAS 263

  Fly   109 ASEMDT-------IVGEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLF 166
            .::|.|       .:...|.....:.:.||     ..||....||||||||:..:|.|:.:.|.|
  Fly   264 TADMATEFAVTKSFLDYSPHGYDFLFLFVV-----FFIFAGGLGNILVCLAVALDRKLQNVTNYF 323

  Fly   167 LASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIK 231
            |.|||||||.|:..||....:...||||..|..:|:.:|..||:..::|||::|.||:.||:.|:
  Fly   324 LFSLAIADLLVSLFVMPMGAIPAFLGYWPLGFTWCNIYVTCDVLACSSSILHMCFISLGRYMGIR 388

  Fly   232 DPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTPTYA 296
            :||......|:|:..|.||.:|::|..||.....||       |:.|.|....|...:.....:.
  Fly   389 NPLGSRHRSTKRLTGIKIAIVWVMAMMVSSSITVLG-------LVNEKNIMPEPNICVINNRAFF 446

  Fly   297 VVSSCISFYFPCVVMIGIYC-------RLYCYAQKHVKSI-------KAVTRP------------ 335
            |..|.::||.|.::|:..|.       :...:|.:|.:|.       :...||
  Fly   447 VFGSLVAFYIPMLMMVTTYALTIPLLRKKARFAAEHPESELFRRLGGRFTLRPQHSQQQLQMFSS 511

  Fly   336 ---------------------GEVAE------------------KQRYKSIR------------- 348
                                 ||:.|                  :||..|.|
  Fly   512 FSGSNNKFLSMGDGNRNFNTEGEMEEGGAPSRRSGVEPAERPLMQQRTASSRSMGTVSFRNVVNG 576

  Fly   349 ----------------------------------------------------------------- 348
                                                                             
  Fly   577 TSGAAGSGRRTTGTAHSSFRFSGAGIFRHSSSSPASSCHSTSTSRSSSFWRKHGGYPNLMDRLAI 641

  Fly   349 ----------------------------------------------------------------- 348
                                                                             
  Fly   642 HLRLSLVPPSSHPNRRASVRVTISQPQLGYPTNVGGNGGRTVGATEVGAGGNGSSAGRTSNSSLG 706

  Fly   349 -----------------------------------------RPKNQPKKF----------KVRNL 362
                                                     |.|.:|.||          .:|.|
  Fly   707 GTSLMKIATIQGPILNQSQAAGGNHMVQKVKPTALKPEEPQRNKVRPFKFAFNRVATPTLNLRFL 771

  Fly   363 HTHSSPYHVS------DHKAAVTVGVIMGVFLICWVPFFCVNITAAFCKTC-IGGQTFKILTWLG 420
            :..|....:|      :.||...:|::...|::||.|||.:||..|.|..| :.........|||
  Fly   772 NNRSKRNSLSANAVATEQKATKVLGLVFFTFVLCWSPFFILNIIFAACPECQVPEHVVNTCLWLG 836

  Fly   421 YSNSAFNPIIYSIFNKEFRDAFKRIL 446
            |.:|..|||||:|||:.||.||.|:|
  Fly   837 YVSSTINPIIYTIFNRTFRAAFIRLL 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	54/131 (41%)
		7tm_1	145..431	CDD:278431	108/551 (20%)
5-HT2A	NP_730859.1	7tm_4	299..>428	CDD:304433	55/135 (41%)
		7tm_1	302..>477	CDD:278431	65/181 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010