Protein Alignment Dop1R1 and 5-HT1B

DIOPT Version :9

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 644
• Identity: 149/644 - (23%)
• Similarity: 231/644 - (35%)
• Gaps: 255/644 - (39%)

  Fly    10 AIAAGVGSVAATVATSTTSSISSSTTIINTSSATTIGGNHTSGSTGFSTNSTLLDADHLPLQLTT 74
            |:|||...|.|::.     .|.....::|.|....:.||.|.          |:|        ||
  Fly     8 AMAAGDDDVPASIL-----EIELPAILLNESLFIELNGNLTQ----------LVD--------TT 49

  Fly    75 AKVDLDIEIDIQLLTNGYDGTTLTSFYNESSWTNASEMDTIVGEEPEPLS-----LVSIVVVGIF 134
            :.:. .|..:..:..||                |::..| :|.:|.|..:     ||.::.:.:.
  Fly    50 SNLS-QIVWNRSINGNG----------------NSNTFD-LVDDEQERAAVEFWLLVKMIAMAVV 96

  Fly   135 LSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQ 199
            |.::|.:::.||:.|..||..||:|:.:.|..:||||:||||||.|||....|.::...||.|.:
  Fly    97 LGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNGWILGPE 161

  Fly   200 FCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPI 264
            .||.|.:.||:|.|||||:|.||:.|||..:.: :.|....|.|...:.|..:|..|..||..|
  Fly   162 LCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWFAALIVSLAP- 224

  Fly   265 SLGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHV--- 326
            ..|...||.....|:.     .|.:.....|.:.::|.:||.|.:|::.:|.::|..|:|.:
  Fly   225 QFGWKDPDYMKRIEEQ-----HCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRR 284

  Fly   327 --KSIKAVTRPGE----VAEKQRYKSIRRPKNQ-----------------------PKKFKV--- 359
              ||........:    |.|.::.:|.||.:.:                       .|:.::
  Fly   285 AQKSFNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRICFG 349

  Fly   360 RNLHT------------------------------------------------------------ 364
            ||.:|
  Fly   350 RNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDADDYR 414

  Fly   365 ---------------HSSPYH-VSDH--------------------------------------- 374
                           |::.:| ::.|
  Fly   415 TSNANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVAGAV 479

  Fly   375 ---------------------------------------------------KAAVTVGVIMGVFL 388
                                                               |||.|:.:|.|.|:
  Fly   480 AGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIITGAFV 544

  Fly   389 ICWVPFFCVNITAAFCKTC-IGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRIL 446
            |||:|||.:.:|.:.||.| |......:..||||.||..||:||:|||.|||.||||||
  Fly   545 ICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRIL 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	54/131 (41%)
		7tm_1	145..431	CDD:278431	107/487 (22%)
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	67/187 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010