Protein Alignment Dop1R1 and mAChR-C

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 102/350 - (29%)
• Similarity: 146/350 - (41%)
• Gaps: 89/350 - (25%)

  Fly   129 VVVGIFLSVLIFLSVAGNILVCLAIYTERSLRR-IGNLFLASLAIADLFVASLVMTFAGV----N 188
            :.:..||.|||   :.||||..:|:.|.|.||. |.|||:.|||::| |...|.:.:..|    :
  Fly    54 LAINAFLFVLI---LGGNILTIVAVRTCRHLRSVISNLFILSLAVSD-FCVGLALPYHLVFYMGS 114

  Fly   189 D--------LLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVA 245
            |        ||.:::.....|            .|:|.|.:|::||||.:...|.|.|::|||||
  Fly   115 DIGAMRGPCLLRFFLLICACC------------VSMLTLISIAVDRYIAVVYALHYRRYMTRRVA 167

  Fly   246 VITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALD-----------LTPTYAVVS 299
            ...|...|.|.|.|:.:|            :|.:.......|..|           :||.:.::.
  Fly   168 YSIIIFNWCLGALVALLP------------VFWNRWPDAQACEFDEVLAPGYIAGVITPGFVIIW 220

  Fly   300 SCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHT 364
            .|         |..:|.|:...|.|....::              :|:  ..|..:...:|||..
  Fly   221 IC---------MFLVYWRIMREASKQALRLR--------------QSV--VYNTDEATTMRNLLL 260

  Fly   365 HSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPI 429
            |      .|.|:...|..|||.|.:||:|:|||.|...|.........:|....|..:|||.|||
  Fly   261 H------PDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAIANSALNPI 319

  Fly   430 IYSIFNKEFRDAFKRILTMRNPWCC 454
            |||..|..||.||.:.|      ||
  Fly   320 IYSWKNSGFRRAFVQTL------CC 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	97/335 (29%)
		TM helix 1	130..156	CDD:320193	10/25 (40%)
		TM helix 2	163..189	CDD:320193	10/29 (34%)
		TM helix 3	201..231	CDD:320193	9/29 (31%)
		TM helix 4	243..265	CDD:320193	9/21 (43%)
		TM helix 5	292..321	CDD:320193	6/28 (21%)
		TM helix 6	371..401	CDD:320193	14/29 (48%)
		TM helix 7	410..435	CDD:320193	11/24 (46%)
mAChR-C	NP_572358.1	7tm_classA_rhodopsin-like	53..325	CDD:410626	94/329 (29%)
		TM helix 1	53..78	CDD:410626	10/26 (38%)
		TM helix 2	86..111	CDD:410626	10/25 (40%)
		TM helix 3	123..153	CDD:410626	11/41 (27%)
		TM helix 4	166..185	CDD:410626	7/18 (39%)
		TM helix 5	204..229	CDD:410626	5/33 (15%)
		TM helix 6	261..291	CDD:410626	15/35 (43%)
		TM helix 7	300..325	CDD:410626	11/24 (46%)