Protein Alignment Dop1R1 and Gpr161

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_017454484.1
• Gene: Gpr161 / 289180
• RGDID: 1563245
• Length: 528
• Species: Rattus norvegicus
• Alignment Length: 364
• Identity: 91/364 - (25%)
• Similarity: 160/364 - (43%)
• Gaps: 50/364 - (13%)

  Fly   104 SSWTNASEMDTIVGEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLA 168
            ||.:...|:..:...|......||..:..|.::||:.|   ||:::.:.:|.:..|..:.|.|:.
  Rat     5 SSLSYRKELSNLTAAEGGEGGAVSEFIAIIIITVLVCL---GNLVIVVTLYKKSYLLTLSNKFVF 66

  Fly   169 SLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDP 233
            ||.:::..::.||:.|...:.:...||||..:|:......::.|:||:|.|..|::|||..:..|
  Rat    67 SLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYP 131

  Fly   234 LRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPL-----IFEDNGKKYPTCALDLTP 293
            :.|...:|...||:.:..|| |.:.:..:|          ||     :..|..|.....|....|
  Rat   132 MVYPMKITGNRAVMALVYIW-LHSLIGCLP----------PLFGWSSVEFDEFKWMCVAAWHREP 185

  Fly   294 TYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFK 358
            .|.|........||.::|  :.|..:.:....||:.|.........|:...:|.|
  Rat   186 GYTVFWQIWCALFPFLIM--LVCYGFIFRVARVKARKVHCGTVVTVEEDAQRSGR---------- 238

  Fly   359 VRNLHTHSSP------------YHVSDHKAAVTVGVIMGVFLICWVPFFCVNIT--AAFCKTCIG 409
             :|..|.:|.            |..:..||.:|:.|::|.|::.|.|:..| ||  |.:.|..:.
  Rat   239 -KNSSTSTSSSGSRRNALQGVVYSANQCKALITILVVIGAFMVTWGPYMVV-ITSEALWGKNYVS 301

  Fly   410 GQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTM 448
            .......|||.::::..:|:||.::||..|   |.:|.|
  Rat   302 PTLETWATWLSFTSAICHPLIYGLWNKTVR---KELLGM 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	82/330 (25%)
		TM helix 1	130..156	CDD:320193	7/25 (28%)
		TM helix 2	163..189	CDD:320193	7/25 (28%)
		TM helix 3	201..231	CDD:320193	10/29 (34%)
		TM helix 4	243..265	CDD:320193	6/21 (29%)
		TM helix 5	292..321	CDD:320193	7/28 (25%)
		TM helix 6	371..401	CDD:320193	11/31 (35%)
		TM helix 7	410..435	CDD:320193	6/24 (25%)
Gpr161	XP_017454484.1	7tmA_GPR161	28..334	CDD:320342	84/336 (25%)
		TM helix 1	28..54	CDD:320342	8/28 (29%)
		TM helix 2	61..86	CDD:320342	7/24 (29%)
		TM helix 3	99..129	CDD:320342	10/29 (34%)
		TM helix 4	141..163	CDD:320342	7/32 (22%)
		TM helix 5	184..213	CDD:320342	7/30 (23%)
		TM helix 6	262..292	CDD:320342	11/30 (37%)
		TM helix 7	302..327	CDD:320342	6/24 (25%)