Protein Alignment Dop1R1 and ser-6

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_741350.1
• Gene: ser-6 / 259560
• WormBaseID: WBGene00021897
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 111/417 - (26%)
• Similarity: 173/417 - (41%)
• Gaps: 122/417 - (29%)

  Fly   128 IVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLG 192
            ::::.:.|.|:....|.||:||...|.|::||:...|..:.||.|:||.:..|::.||.:.:...
 Worm     1 MILLSLTLGVVNCFVVIGNLLVFYVILTKKSLQTSTNHLVLSLTISDLLLGILILPFAIIQEHSN 65

  Fly   193 YWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIW---L 254
            .||||...|..|::.||..|||||.||.|||.|||:.::.|::|....:.:|..:....:|   |
 Worm    66 EWIFGHFGCRLWLSVDVFLSTASIYNLLAISFDRYMAVRQPIKYPIISSTKVVRLMTFLVWFCSL 130

  Fly   255 LAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTPT-----YAVVSSCISFYFPCVVMIGI 314
            |.|.:.||.::|..|..:            ||  .|..||     |.:.|:..||..|..||:.:
 Worm   131 LLAVILFVLLTLNAHDSE------------PT--KDCQPTSLPSMYIIFSAMASFIVPAFVMVIL 181

  Fly   315 YCRLY------------------------------------------------------------ 319
            ..|::
 Worm   182 NVRIFQTVLHTSRTMTVKSKNGSLRVHRRKEPIIPVKKHDKYETRLSHEEECVGSPSKEVIDPIP 246

  Fly   320 --CYAQKHVKSIKAVTRP-----------------------GEVAEKQRYKSIRRPK-NQPKKFK 358
              ...:||.|| .||..|                       ..:.:..|..::|.|. :..||..
 Worm   247 VVAVVEKHHKS-SAVDAPAIRSFLTHTVVFGVLEAKKTNIINHITQWWRRSTVRSPNPSTRKKCM 310

  Fly   359 VRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAF--CKT---CIGGQTFKILTW 418
            .|:|.|        :.:.|.|.|:::..|::||:||..:.:..|:  |..   ||....|....|
 Worm   311 RRSLRT--------EIRVARTTGIVVAAFIVCWIPFTTIYVLQAYAVCTVAAGCIPASLFTTAFW 367

  Fly   419 LGYSNSAFNPIIYSIFNKEFRDAFKRI 445
            |||||||.|||:|:.|:::||.|.||:
 Worm   368 LGYSNSAVNPILYAAFSRDFRIALKRL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	108/410 (26%)
		TM helix 1	130..156	CDD:320193	8/25 (32%)
		TM helix 2	163..189	CDD:320193	9/25 (36%)
		TM helix 3	201..231	CDD:320193	17/29 (59%)
		TM helix 4	243..265	CDD:320193	7/24 (29%)
		TM helix 5	292..321	CDD:320193	10/95 (11%)
		TM helix 6	371..401	CDD:320193	8/29 (28%)
		TM helix 7	410..435	CDD:320193	13/24 (54%)
ser-6	NP_741350.1	7tmA_amine_R-like	3..391	CDD:320098	108/410 (26%)
		TM helix 1	3..29	CDD:320098	8/25 (32%)
		TM helix 2	36..63	CDD:320098	9/26 (35%)
		TM helix 3	74..104	CDD:320098	17/29 (59%)
		TM helix 4	116..136	CDD:320098	5/19 (26%)
		TM helix 5	158..314	CDD:320098	21/156 (13%)
		TM helix 6	315..345	CDD:320098	9/37 (24%)
		TM helix 7	359..384	CDD:320098	13/24 (54%)