Protein Alignment Dop1R1 and Taar7b

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001010827.1
• Gene: Taar7b / 209517
• MGIID: 3527438
• Length: 358
• Species: Mus musculus
• Alignment Length: 315
• Identity: 98/315 - (31%)
• Similarity: 146/315 - (46%)
• Gaps: 40/315 - (12%)

  Fly   141 LSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWV 205
            |:|.||:||..:|...|.|....|..:.|||.||..|...||.|:.|..:.|.|.||..:|....
Mouse    60 LAVCGNLLVMTSILHFRQLHSPANFLVVSLACADFLVGLTVMPFSTVRSVEGCWYFGESYCKLHT 124

  Fly   206 AFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHR 270
            .|||.....||.:||.||:||||.:.|||.|....|..|:...|...|||:....|..:..|.:.
Mouse   125 CFDVSFCYCSIFHLCFISVDRYIAVSDPLTYPTRFTAFVSGKCITFSWLLSTIYGFSLLYTGANE 189

  Fly   271 PDQPLIFED--------NGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVK 327
            ..    .||        .|     |.|.:..::..::..: |..|.:|||.:|.:::..|::..:
Mouse   190 AG----LEDLVSALTCVGG-----CQLAVNQSWVFINFLL-FLIPTLVMITVYSKIFLIAKQQAQ 244

  Fly   328 SIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWV 392
            :|       |...||..::....|::..|               .:.|||.|:|:.:..||:.|:
Mouse   245 NI-------EKMSKQTARASDSYKDRVAK---------------RERKAAKTLGIAVAAFLLSWL 287

  Fly   393 PFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILT 447
            |:|..:|..||.........::||.|:.|.|||.||:||:.|...||.|.|.|::
Mouse   288 PYFIDSIIDAFLGFITPTYVYEILVWIAYYNSAMNPLIYAFFYPWFRKAIKLIVS 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	95/308 (31%)
		TM helix 1	130..156	CDD:320193	7/14 (50%)
		TM helix 2	163..189	CDD:320193	11/25 (44%)
		TM helix 3	201..231	CDD:320193	14/29 (48%)
		TM helix 4	243..265	CDD:320193	6/21 (29%)
		TM helix 5	292..321	CDD:320193	6/28 (21%)
		TM helix 6	371..401	CDD:320193	11/29 (38%)
		TM helix 7	410..435	CDD:320193	11/24 (46%)
Taar7b	NP_001010827.1	7tm_GPCRs	49..337	CDD:475119	95/308 (31%)
		TM helix 1	50..74	CDD:410628	7/13 (54%)
		TM helix 2	83..105	CDD:410628	10/21 (48%)
		TM helix 3	121..143	CDD:410628	8/21 (38%)
		TM helix 4	166..182	CDD:410628	5/15 (33%)
		TM helix 5	210..233	CDD:410628	5/23 (22%)
		TM helix 6	272..294	CDD:410628	8/21 (38%)
		TM helix 7	305..330	CDD:410628	11/24 (46%)