Protein Alignment Dop1R1 and Taar2

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001007267.1
• Gene: Taar2 / 209512
• MGIID: 2685071
• Length: 339
• Species: Mus musculus
• Alignment Length: 395
• Identity: 102/395 - (25%)
• Similarity: 162/395 - (41%)
• Gaps: 84/395 - (21%)

  Fly    97 LTSFYNESSWTNASEMDTIVGEEPE-PLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLR 160
            :.||..:....:.||...  |..|| ..||.....:...::..||:::.||:.:.::|...:.|.
Mouse     1 MASFEAQQETFDCSEYGN--GSCPENERSLGVRAAMYSLMACAIFITIFGNLAMIISISYFKQLH 63

  Fly   161 RIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMD 225
            ...||.:.|:|:.|..:...:|.::.|..:...|.||..||....:||:|.|..||.:||::::|
Mouse    64 TPTNLLILSMAVTDFLLGFTIMPYSMVRSVENCWYFGLTFCKIHYSFDLMLSITSIFHLCSVAVD 128

  Fly   226 RYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALD 290
            |:..|..||.|...:|..|....:...|.:....:|                   |..:.....|
Mouse   129 RFYAICHPLHYCTKMTIPVVRRLLLVCWSVPGAFAF-------------------GVVFSEAYAD 174

  Fly   291 LTPTYAVVSSCIS------------------FYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGE 337
            ....|.::.:|.|                  |:.|..:|:|||.:::..::||.:.|..:
Mouse   175 GIEGYDILVACSSSCPVMFNKLWGTTLFVAGFFTPSSMMVGIYGKIFAVSKKHARVIDNL----- 234

  Fly   338 VAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAA 402
                        |:||..:.:             .|.|||.|:|::|||||:||.|.|...:...
Mouse   235 ------------PENQNNQMR-------------KDKKAAKTLGIVMGVFLLCWFPCFFTILLDP 274

  Fly   403 FCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMRNPWCCAQDVGNI---HPR 464
            |.........|..|||.||.||..||:||..|...||.|.|.||           :|.|   |..
Mouse   275 FLNFSTPAVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIL-----------LGKIFSSHFH 328

  Fly   465 NSDRF 469
            |::.|
Mouse   329 NTNLF 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	84/329 (26%)
		TM helix 1	130..156	CDD:320193	5/25 (20%)
		TM helix 2	163..189	CDD:320193	7/25 (28%)
		TM helix 3	201..231	CDD:320193	11/29 (38%)
		TM helix 4	243..265	CDD:320193	3/21 (14%)
		TM helix 5	292..321	CDD:320193	9/46 (20%)
		TM helix 6	371..401	CDD:320193	15/29 (52%)
		TM helix 7	410..435	CDD:320193	12/24 (50%)
Taar2	NP_001007267.1	7tmA_TAAR2_3_4	33..314	CDD:320437	84/329 (26%)
		TM helix 1	33..59	CDD:320437	5/25 (20%)
		TM helix 2	66..92	CDD:320437	7/25 (28%)
		TM helix 3	104..134	CDD:320437	11/29 (38%)
		TM helix 4	146..169	CDD:320437	4/41 (10%)
		TM helix 5	194..223	CDD:320437	6/28 (21%)
		TM helix 6	244..273	CDD:320437	15/28 (54%)
		TM helix 7	282..307	CDD:320437	12/24 (50%)