Protein Alignment Dop1R1 and ser-2

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001024339.1
• Gene: ser-2 / 182110
• WormBaseID: WBGene00004777
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 398
• Identity: 117/398 - (29%)
• Similarity: 189/398 - (47%)
• Gaps: 79/398 - (19%)

  Fly   120 PEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTF 184
            |..:..|.:|:..|...|:|.::|.||.||.:|:::.|.|:::.|.||.|||.:||.||..||..
 Worm    49 PSIIPTVELVLGTITYLVIIAMTVVGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPL 113

  Fly   185 AGVNDLL-GYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVIT 248
            ..|..|. |.|:.|...|..:...|::..|:||||||||::|||..|.:|:.|.:..|.:...|.
 Worm   114 HVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIV 178

  Fly   249 IAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIG 313
            |..:|:|:..:|..|| :|.:...:.:: ||      :|.|.....:.|.|:..||:.|.:||:.
 Worm   179 IVIVWILSMLISVPPI-IGWNNWQENMM-ED------SCGLSTEKAFVVFSAAGSFFLPLLVMVV 235

  Fly   314 IYCRLYCYAQKHVK----------------------------SIKAVTRPGEVAEK--------- 341
            :|.:::..|::.::                            |:::......|.||
 Worm   236 VYVKIFISARQRIRTNRGRSALMRIQNAEGDDDYRKMSIKRASVESARTSSRVGEKTPLVIADGQ 300

  Fly   342 -------------------QRYKSIRRPKNQPKKFKVRNL---HTHSSPYHV----------SDH 374
                               :..|.::...|...|.||:::   ..:.:|..|          .:.
 Worm   301 TTVTTLAAHSTDGGSLPKDETTKHMKYHNNGSCKVKVKDVKEDEGNPNPTAVLRKREKISVAKEK 365

  Fly   375 KAAVTVGVIMGVFLICWVPFFCVNITAAFCKTC-IGGQTFKILTWLGYSNSAFNPIIYSIFNKEF 438
            :||.|:.||:.||..||:|||...:...||:|| :..:..:..|||||.||:.||.:|.|.|.||
 Worm   366 RAAKTIAVIIFVFSFCWLPFFVAYVIRPFCETCKLHAKVEQAFTWLGYINSSLNPFLYGILNLEF 430

  Fly   439 RDAFKRIL 446
            |.|||:||
 Worm   431 RRAFKKIL 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	109/382 (29%)
		TM helix 1	130..156	CDD:320193	9/25 (36%)
		TM helix 2	163..189	CDD:320193	13/25 (52%)
		TM helix 3	201..231	CDD:320193	14/29 (48%)
		TM helix 4	243..265	CDD:320193	6/21 (29%)
		TM helix 5	292..321	CDD:320193	8/28 (29%)
		TM helix 6	371..401	CDD:320193	13/39 (33%)
		TM helix 7	410..435	CDD:320193	11/24 (46%)
ser-2	NP_001024339.1	7tmA_tyramine_octopamine_R-like	58..434	CDD:320188	110/383 (29%)
		TM helix 1	59..85	CDD:320188	9/25 (36%)
		TM helix 2	92..118	CDD:320188	13/25 (52%)
		TM helix 3	131..161	CDD:320188	14/29 (48%)
		TM helix 4	173..196	CDD:320188	7/23 (30%)
		TM helix 5	214..243	CDD:320188	8/28 (29%)
		TM helix 6	362..392	CDD:320188	12/29 (41%)
		TM helix 7	402..427	CDD:320188	11/24 (46%)