Protein Alignment Dop1R1 and tyra-2

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001033537.1
• Gene: tyra-2 / 180970
• WormBaseID: WBGene00017157
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 441
• Identity: 114/441 - (25%)
• Similarity: 186/441 - (42%)
• Gaps: 124/441 - (28%)

  Fly   129 VVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGY 193
            ::.|..|.:|:..::..|.||.:.:|....|:.:.||.:.:||.:||.:..:|:..:.|..:.|.
 Worm    19 ILKGSALFLLVLWTIFANSLVFIVLYKNPRLQTVPNLLVGNLAFSDLALGLIVLPLSSVYAIAGE 83

  Fly   194 WIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAF 258
            |:|....|:.:|:.|::||||||.||..:.:|||..|..|:.|.....:|.|.|.|.::|:.:|.
 Worm    84 WVFPDALCEVFVSADILCSTASIWNLSIVGLDRYWAITSPVAYMSKRNKRTAGIMILSVWISSAL 148

  Fly   259 VSFVPISLGIHRPDQP--LIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLY-- 319
            :|..|: ||..:..|.  ||:|.|........||| |:|.|.|:..||:.|.::|..:|.::|
 Worm   149 ISLAPL-LGWKQTAQTPNLIYEKNNTVRQCTFLDL-PSYTVYSATGSFFIPTLLMFFVYFKIYQA 211

  Fly   320 --------CYAQ----------KHVKS-------------------------------------- 328
                    .|.|          ||::|
 Worm   212 FAKHRARQIYRQKLAVSSHVIRKHIESTILHEISHVLPTSDEFAKEEEEEEDSESSGQVENGLGN 276

  Fly   329 -----------------------------IKAVTRPGEVAEKQR--------------------- 343
                                         ...||.|.|....:|
 Worm   277 GNDAIIEEDECEDEDSDEKRDDHTSMTTVTATVTGPTEAPYMKREAKISKSVPIEKESAIQKREA 341

  Fly   344 ----------YKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTV-GVIMGVFLICWVPFFCV 397
                      |:.::|.||:.::...::|.........:..:..|.| |:|:|.|.:||.|||.:
 Worm   342 KPMRSVMAISYEKVKRHKNRKERIYRKSLQRKPKAISAAKERRGVKVLGIILGCFTVCWAPFFTM 406

  Fly   398 NITAAFCKTCIGGQTFKI-LTWLGYSNSAFNPIIYSIFNKEFRDAFKRILT 447
            .:...|||.|......:: :|||||||||.|||||::||::::.|.||:.|
 Worm   407 YVLVQFCKDCSPNAHIEMFITWLGYSNSAMNPIIYTVFNRDYQIALKRLFT 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	110/433 (25%)
		TM helix 1	130..156	CDD:320193	7/25 (28%)
		TM helix 2	163..189	CDD:320193	8/25 (32%)
		TM helix 3	201..231	CDD:320193	14/29 (48%)
		TM helix 4	243..265	CDD:320193	8/21 (38%)
		TM helix 5	292..321	CDD:320193	10/38 (26%)
		TM helix 6	371..401	CDD:320193	11/30 (37%)
		TM helix 7	410..435	CDD:320193	14/25 (56%)
tyra-2	NP_001033537.1	7tmA_amine_R-like	20..452	CDD:320098	110/433 (25%)
		TM helix 1	20..46	CDD:320098	7/25 (28%)
		TM helix 2	53..80	CDD:320098	8/26 (31%)
		TM helix 3	91..121	CDD:320098	14/29 (48%)
		TM helix 4	133..153	CDD:320098	7/19 (37%)
		TM helix 5	182..379	CDD:320098	26/197 (13%)
		TM helix 6	380..410	CDD:320098	11/29 (38%)
		TM helix 7	420..445	CDD:320098	14/24 (58%)