Protein Alignment Dop1R1 and Htr7

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001334371.1
• Gene: Htr7 / 15566
• MGIID: 99841
• Length: 470
• Species: Mus musculus
• Alignment Length: 354
• Identity: 115/354 - (32%)
• Similarity: 178/354 - (50%)
• Gaps: 66/354 - (18%)

  Fly   126 VSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDL 190
            |..||:|..|:::..|::|||.||.:::...:.||:..|..:.|||:|||.||..||.|..|.||
Mouse    82 VEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDL 146

  Fly   191 L-GYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWL 254
            : |.||||..||:.::|.||||.||||:.||.||:|||:.|..||.|......:.....|.::||
Mouse   147 IGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWL 211

  Fly   255 LAAFVSFVPI---SLGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYC 316
            |:|.::..|:   :..::.....||.:|.|             |.:.|:.::||.|..||:.:|.
Mouse   212 LSASITLPPLFGWAQNVNDDKVCLISQDFG-------------YTIYSTAVAFYIPMSVMLFMYY 263

  Fly   317 RLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPK-------------------------K 356
            ::|..|:|.             |.|.::...  |:.||:                         |
Mouse   264 QIYKAARKS-------------AAKHKFSGF--PRVQPESVISLNGVVKLQKEVEECANLSRLLK 313

  Fly   357 FKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAF-CKT---CIGGQTFKILT 417
            .:.:|:....     .:.|||.|:|:|:|.|.:||:|||.::....| |.|   ||.....:...
Mouse   314 HERKNISIFK-----REQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCL 373

  Fly   418 WLGYSNSAFNPIIYSIFNKEFRDAFKRIL 446
            ||||:||..||.||:.||::.|..::.:|
Mouse   374 WLGYANSLINPFIYAFFNRDLRTTYRSLL 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	112/344 (33%)
		TM helix 1	130..156	CDD:320193	9/25 (36%)
		TM helix 2	163..189	CDD:320193	13/25 (52%)
		TM helix 3	201..231	CDD:320193	17/29 (59%)
		TM helix 4	243..265	CDD:320193	6/24 (25%)
		TM helix 5	292..321	CDD:320193	9/28 (32%)
		TM helix 6	371..401	CDD:320193	13/29 (45%)
		TM helix 7	410..435	CDD:320193	10/24 (42%)
Htr7	NP_001334371.1	7tmA_5-HT7	100..398	CDD:320452	108/330 (33%)
		TM helix 2	119..145	CDD:320452	13/25 (52%)
		TM helix 3	158..188	CDD:320452	17/29 (59%)
		TM helix 4	200..222	CDD:320452	6/21 (29%)
		TM helix 5	239..268	CDD:320452	11/41 (27%)
		TM helix 6	323..353	CDD:320452	13/34 (38%)
		TM helix 7	366..391	CDD:320452	10/24 (42%)