Protein Alignment Dop1R1 and Drd5

DIOPT Version :9

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_038531.1
• Gene: Drd5 / 13492
• MGIID: 94927
• Length: 478
• Species: Mus musculus
• Alignment Length: 416
• Identity: 157/416 - (37%)
• Similarity: 218/416 - (52%)
• Gaps: 65/416 - (15%)

  Fly   117 GEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLR-RIGNLFLASLAIADLFVASL 180
            |....||....:|..|: |::||..::.||:|||.||...|.|| ::.|:|:.|||::|||||.|
Mouse    28 GGSAAPLGPAQVVTAGL-LTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALL 91

  Fly   181 VMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVA 245
            ||.:..|.::.|||.||| |||.|||||:|||||||||||.||:|||..|..|.||.|.:|:|||
Mouse    92 VMPWKAVAEVAGYWPFGA-FCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVA 155

  Fly   246 VITIAAIWLLAAFVSFVPISLGIHRPD------QPLI---------FEDNGKKYPTCALDLTPTY 295
            ::.:|..|.|:..:||:|:.|..||..      :.|:         :|.:|:. ..|...|..||
Mouse   156 LVMVALAWTLSILISFIPVQLNWHRDKAGSQGREGLLSNETPWEEGWELDGRT-ENCDSSLNRTY 219

  Fly   296 AVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRP--------KN 352
            |:.||.||||.|..:||..|.|:|..||..::.|.::.|..|.|:..|.:....|        |.
Mouse   220 AISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGACEPDPSLRASIKK 284

  Fly   353 QPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCKT----------- 406
            :.|.||                    |:.||||||:.||:|||.:|....||.:
Mouse   285 ETKVFK--------------------TLSVIMGVFVCCWLPFFILNCMVPFCSSGDAQGPRTGFP 329

  Fly   407 CIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRI-----LTMRNPWCCAQDVGNIHPRNS 466
            |:...||.|..|.|::||:.|||||: ||.:||..|.::     |..|.|.........:...|.
Mouse   330 CVSETTFDIFVWFGWANSSLNPIIYA-FNADFRKVFAQLLGCSHLCFRTPVQTVNISNELISYNQ 393

  Fly   467 DR-FITDYAAKNVVVMNSGRSSAELE 491
            |. |..:.||..|.::.:..||.:.|
Mouse   394 DTVFHREIAAAYVHMIPNAVSSGDRE 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	72/132 (55%)
		7tm_1	145..431	CDD:278431	130/320 (41%)
Drd5	NP_038531.1	7tm_1	55..354	CDD:278431	130/320 (41%)
		7tm_4	<121..>173	CDD:304433	29/51 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..446		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	225	1.000	Domainoid score	I2525
eggNOG	1	0.900	-	-		E33208_3B9BF
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3277
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001416
OrthoInspector	1	1.000	-	-		otm42907
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4063
SonicParanoid	1	1.000	-	-		X883
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.850