Protein Alignment Dop1R1 and Oct-TyrR

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_061506991.1
• Gene: Oct-TyrR / 1273444
• VectorBaseID: AGAMI1_002266
• Length: 644
• Species: Anopheles gambiae
• Alignment Length: 625
• Identity: 141/625 - (22%)
• Similarity: 213/625 - (34%)
• Gaps: 275/625 - (44%)

  Fly    82 EIDIQL---------------LTNGYD--GTTLTSFYNESSWTNASEMDTIVGEEPEPLSLVSIV 129
            |:||.|               .|.|.|  |..|.:.|.    .|.|::..::...|:|...:...
Mosquito    37 ELDILLRHEGSIPAVSLAGLTATLGLDSNGELLGANYG----ANGSDLSELLDGCPKPDDTLYPT 97

  Fly   130 VVGI--------------FLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASL 180
            :.||              .|:::|.:::.|||||.|:::|.:.||.:.|.|:.|||:|||.||.|
Mosquito    98 MFGIDLAVPQWEAIGTALILTLIIIITIVGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVAIL 162

  Fly   181 VMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVA 245
            |:.......|||.|.||...|..|:..||:|.||||||||||::|||..|.||:.|.:..|....
Mosquito   163 VLPLNVAYSLLGRWEFGIHVCKMWLTSDVLCCTASILNLCAIALDRYWAITDPINYAQKRTLERV 227

  Fly   246 VITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVV 310
            :..||.:|:|:..:|..|:   |...|.|   |:...::| |.|.....|.:.||..||:.|..:
Mosquito   228 LALIAGVWVLSLVISSPPL---IGWNDWP---EEFSSEFP-CQLTSNQGYVIYSSLGSFFIPLAI 285

  Fly   311 MIGIYCRLYCYAQKHV--------------KSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRN 361
            |..:|..:|...::.:              :||..|...||       |.:....:|.::.:.::
Mosquito   286 MTIVYIEIYIATRRRLRERAQASKINTLASRSIGMVAGNGE-------KELTTTHHQQQQQQQQH 343

  Fly   362 LHTHSSPYHVSDH---------------------------------------------------- 374
            .|.|.|.:|...|
Mosquito   344 QHHHQSHHHQDGHAIQHDQESISSETNNHNEQTDTGSGGPVLAGSGKPNKKGHLRFGGYLGRALG 408

  Fly   375 ----------------------------------------------------------------- 374
                                                                             
Mosquito   409 GAAGRHRKKQHHRKRPGDGPAEEGEDGRPHRLAASALHQREDDSVTDNPDHSGSGDSGGGVGKAP 473

  Fly   375 ----------------------------------------------------------------- 374
                                                                             
Mosquito   474 LDAAHPSALLPPTGNCDMTGGSATGEPAPRNGASNNHHQREVGFHESTAELMVVAAAAPPTTRLG 538

  Fly   375 -----------------------------KAAVTVGVIMGVFLICWVPFFCVNITAAFCKTCI-G 409
                                         :||.|:|:|||||::||:|||.:.:...||.:|. .
Mosquito   539 GRLKQSFRKPGGINQFIEEKQKISLSKERRAARTLGIIMGVFVVCWLPFFLMYVILPFCPSCCPT 603

  Fly   410 GQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMR 449
            .:....:|||||.|||.|||||:|||.::|.||||:|.::
Mosquito   604 NKLINFITWLGYINSALNPIIYTIFNLDYRRAFKRLLGIK 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	122/551 (22%)
		TM helix 1	130..156	CDD:320193	10/39 (26%)
		TM helix 2	163..189	CDD:320193	12/25 (48%)
		TM helix 3	201..231	CDD:320193	18/29 (62%)
		TM helix 4	243..265	CDD:320193	6/21 (29%)
		TM helix 5	292..321	CDD:320193	9/28 (32%)
		TM helix 6	371..401	CDD:320193	15/240 (6%)
		TM helix 7	410..435	CDD:320193	14/24 (58%)
Oct-TyrR	XP_061506991.1	None