Protein Alignment Dop1R1 and Adrb3

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_038490.2
• Gene: Adrb3 / 11556
• MGIID: 87939
• Length: 400
• Species: Mus musculus
• Alignment Length: 345
• Identity: 120/345 - (34%)
• Similarity: 178/345 - (51%)
• Gaps: 33/345 - (9%)

  Fly   136 SVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQF 200
            ::|...:|.||:||.:||.....|:.|.|:|:.|||.|||.|..|||.......|.|:|..|...
Mouse    42 ALLALATVGGNLLVIIAIARTPRLQTITNVFVTSLAAADLVVGLLVMPPGATLALTGHWPLGETG 106

  Fly   201 CDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPIS 265
            |:.|.:.||:|.||||..|||:::|||:.:.:|||||..||:|.|...:..:|:::|.|||.||.
Mouse   107 CELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSAAVSFAPIM 171

  Fly   266 LGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYA--QKHVKS 328
            ....|.......::.......|:......||::||.:|||.|.:||:.:|.|::..|  |:|:..
Mouse   172 SQWWRVGADAEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRHLLR 236

  Fly   329 IKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHV-------------SDHKAAVTV 380
                      .|..|:.....|.:..:........|.::|..|             .:|:|..|:
Mouse   237 ----------RELGRFSPEESPPSPSRSPSPATGGTPAAPDGVPPCGRRPARLLPLREHRALRTL 291

  Fly   381 GVIMGVFLICWVPFFCVNITAAFC-KTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKR 444
            |:|||:|.:||:|||..|:..|.. .:.:....|..|.||||:||||||:|| ..:.:|||||:|
Mouse   292 GLIMGIFSLCWLPFFLANVLRALAGPSLVPSGVFIALNWLGYANSAFNPVIY-CRSPDFRDAFRR 355

  Fly   445 ILTMRNPWCCAQDVGNIHPR 464
            :|      |.....|...||
Mouse   356 LL------CSYGGRGPEEPR 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	112/321 (35%)
		TM helix 1	130..156	CDD:320193	8/19 (42%)
		TM helix 2	163..189	CDD:320193	12/25 (48%)
		TM helix 3	201..231	CDD:320193	15/29 (52%)
		TM helix 4	243..265	CDD:320193	8/21 (38%)
		TM helix 5	292..321	CDD:320193	12/28 (43%)
		TM helix 6	371..401	CDD:320193	15/42 (36%)
		TM helix 7	410..435	CDD:320193	14/24 (58%)
Adrb3	NP_038490.2	7tm_GPCRs	48..353	CDD:475119	111/315 (35%)
		TM helix 2	70..92	CDD:410628	12/21 (57%)
		TM helix 3	108..130	CDD:410628	11/21 (52%)
		TM helix 4	153..169	CDD:410628	5/15 (33%)
		TM helix 5	199..222	CDD:410628	10/22 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..271		5/29 (17%)
		TM helix 6	288..310	CDD:410628	11/21 (52%)
		TM helix 7	322..347	CDD:410628	14/25 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..400		120/345 (35%)