Protein Alignment Dop1R1 and Taar1

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_599155.1
• Gene: Taar1 / 113914
• RGDID: 621621
• Length: 332
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 109/355 - (30%)
• Similarity: 163/355 - (45%)
• Gaps: 61/355 - (17%)

  Fly   124 SLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVN 188
            ||.|::      |::|..::.||::|.::|...:.|....|..|.|:|:.|..:..|||.::.|.
  Rat    24 SLYSLI------SLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVR 82

  Fly   189 DLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIW 253
            .:...|.||..||....:.|:|.|:||||:|..||:|||..:.|||||...:......:.|...|
  Rat    83 TVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISW 147

  Fly   254 LLAAFVSFVPISL-----GIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCI----SFYFPCV 309
            .|.|..:|..|.|     |:.......:|         |.....|.::.||..:    |||.|..
  Rat   148 SLPAVFAFGMIFLELNLEGVEEQYHNQVF---------CLRGCFPFFSKVSGVLAFMTSFYIPGS 203

  Fly   310 VMIGIYCRLYCYAQKHVKSI-KAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSD 373
            ||:.:|.|:|..|:...:|| :|..:.|...|.      |.|:::                   :
  Rat   204 VMLFVYYRIYFIAKGQARSINRANLQVGLEGES------RAPQSK-------------------E 243

  Fly   374 HKAAVTVGVIMGVFLICWVPFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEF 438
            .|||.|:|:::||||:||.|||...:...|....|.......|.|.||.||||||::|:.|...|
  Rat   244 TKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWF 308

  Fly   439 RDAFKRILTMRNPWCCAQDVGNIHPRNSDR 468
            |.|.|.:|           .|.|..::|.|
  Rat   309 RRALKMVL-----------FGKIFQKDSSR 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	99/321 (31%)
		TM helix 1	130..156	CDD:320193	6/25 (24%)
		TM helix 2	163..189	CDD:320193	9/25 (36%)
		TM helix 3	201..231	CDD:320193	14/29 (48%)
		TM helix 4	243..265	CDD:320193	5/21 (24%)
		TM helix 5	292..321	CDD:320193	12/32 (38%)
		TM helix 6	371..401	CDD:320193	14/29 (48%)
		TM helix 7	410..435	CDD:320193	11/24 (46%)
Taar1	NP_599155.1	7tmA_TAAR1	25..312	CDD:320438	101/326 (31%)
		TM helix 1	25..50	CDD:320438	8/30 (27%)
		TM helix 2	57..83	CDD:320438	9/25 (36%)
		TM helix 3	95..125	CDD:320438	14/29 (48%)
		TM helix 4	137..160	CDD:320438	6/22 (27%)
		TM helix 5	186..215	CDD:320438	11/28 (39%)
		TM helix 6	241..271	CDD:320438	14/48 (29%)
		TM helix 7	280..305	CDD:320438	11/24 (46%)