DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dop1R1 and LOC100909683

DIOPT Version :9

Sequence 1:	NP_001262563.1	Gene:	Dop1R1 / 41726	FlyBaseID:	FBgn0011582	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_003750339.3	Gene:	LOC100909683 / 100909683	RGDID:	6502391	Length:	316	Species:	Rattus norvegicus

Alignment Length:	360	Identity:	73/360 - (20%)
Similarity:	128/360 - (35%)	Gaps:	135/360 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 LSVLIFL-SVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGA 198
            |.:|::| ::.||:.:..||:||..|.....|||.:|:|::: :.::|:|...::|||     ..
  Rat    31 LYLLMYLFTLLGNLFIMAAIWTEHRLHTPMYLFLCALSISEI-LFTVVITPRMLSDLL-----ST 89

  Fly   199 QFCDTWVAFDVMCS-----------TASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAI 252
            ....|::|    |:           |.|.| |..:..|||:.|..||.|...::.:.....:|..
  Rat    90 HRSITFIA----CANQLFFSFTFGYTHSFL-LVVMGYDRYVAICRPLHYHVLMSIQGCARLVAWS 149

  Fly   253 WLLAAFVSFVPISLGIHRPDQPLIF-----EDNGKKYPTC----ALDLT-------PTYAVVSSC 301
            |   |..|.:.::|.|      :||     :.|...:..|    .|.|.       .|.||:..|
  Rat   150 W---AGGSLIGMTLTI------VIFHLTFCDSNVIHHFLCHVFSLLKLACGEGTAFVTIAVILVC 205

  Fly   302 ISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKF--------- 357
            ::....|:|.|.:         .::..:.|:.|            |...:.:.|.|
  Rat   206 VTPLIGCLVFIVL---------SYIFIVAAILR------------IPSTEGRHKTFSTCASHLTV 249

  Fly   358 -------------KVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCKTCIG 409
                         |.|.||             ::....:|......:.||
  Rat   250 VIVHYGFASLIYLKSRGLH-------------SLYTDTLMSTTYTVFTPF--------------- 286

  Fly   410 GQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKR 444
                            .:|||:|:.|||.::|..:
  Rat   287 ----------------LSPIIFSLRNKELKNAINK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	38/142 (27%)
Dop1R1	NP_001262563.1	7tm_1	145..431	CDD:278431	64/334 (19%)
LOC100909683	XP_003750339.3	7tmA_OR10A-like	42..303	CDD:320353	69/345 (20%)
		TM helix 2	61..83	CDD:320353	7/22 (32%)
		TM helix 3	99..121	CDD:320353	4/22 (18%)
		TM helix 4	144..160	CDD:320353	4/18 (22%)
		TM helix 5	198..221	CDD:320353	7/31 (23%)
		TM helix 6	240..262	CDD:320353	1/21 (5%)
		TM helix 7	271..296	CDD:320353	7/55 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100