Protein Alignment Dop1R1 and htr7

DIOPT Version :10

• Sequence 1: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_003199632.2
• Gene: htr7 / 100536080
• -ID: -
• Length: 410
• Species: Danio rerio
• Alignment Length: 396
• Identity: 125/396 - (31%)
• Similarity: 198/396 - (50%)
• Gaps: 63/396 - (15%)

  Fly    83 IDIQLLTNGYDGTTLTSFYNESSWTNASEMD--TIVGEEPEPLSLVSIVVVGIFLSVLIFLSVAG 145
            :|:..|...:|.||        :....|.||  |..|........|..|::|..|::|.||:|.|
Zfish    22 MDVSFLNKIHDTTT--------TLPTPSFMDNGTRCGVPILSYGHVEKVLIGGVLTMLTFLTVCG 78

  Fly   146 NILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLL-GYWIFGAQFCDTWVAFDV 209
            |:||.:::...:.|::..|..:.|||:|||.||.:||.|..:.||: |.||||..||:.::|.||
Zfish    79 NLLVVISVCFVKKLKQPSNYLIVSLAVADLSVAVVVMPFVSITDLIGGQWIFGRVFCNVFIAMDV 143

  Fly   210 MCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPI---SLGIHRP 271
            ||.||||:.||.||:|||:.|..||.|....:.:.....:.::|||:|.::..|:   :..::..
Zfish   144 MCCTASIMTLCVISIDRYLGITKPLTYPVRQSGKCMAKIVLSVWLLSASITLPPLFGWAQNVNDD 208

  Fly   272 DQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQ----KHV------ 326
            :..||.:|.|             |.:.|:.::||.|..||:.:|.|:|..|:    ||.
Zfish   209 NVCLISQDLG-------------YTIYSTAVAFYIPMSVMLIMYYRIYRVAKDSAAKHTIAGFPK 260

  Fly   327 ----KSIKAVTR----PGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVI 383
                :|:..||.    ..||.|...:.  |..|:..|...:          ...:.|||.|:|::
Zfish   261 AEDEESMNCVTAALKLQREVEECVSFS--RLLKSDRKNISI----------FKREQKAAATLGIV 313

  Fly   384 MGVFLICWVPFFCVNITAAF-----CKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFK 443
            :|.|.:||:|||.::....|     | :|:.....:.|.||||:||..||.||:.||::.|..:.
Zfish   314 VGAFAVCWMPFFLLSTARPFICGLQC-SCVPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYH 377

  Fly   444 RILTMR 449
            .::..|
Zfish   378 NLIRCR 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R1	NP_001262563.1	7tmA_Ap5-HTB1-like	130..442	CDD:320193	112/338 (33%)
		TM helix 1	130..156	CDD:320193	10/25 (40%)
		TM helix 2	163..189	CDD:320193	12/25 (48%)
		TM helix 3	201..231	CDD:320193	17/29 (59%)
		TM helix 4	243..265	CDD:320193	5/24 (21%)
		TM helix 5	292..321	CDD:320193	10/28 (36%)
		TM helix 6	371..401	CDD:320193	12/29 (41%)
		TM helix 7	410..435	CDD:320193	11/24 (46%)
htr7	XP_003199632.2	7tmA_5-HT7	62..376	CDD:320452	113/339 (33%)
		TM helix 1	63..89	CDD:320452	10/25 (40%)
		TM helix 2	96..122	CDD:320452	12/25 (48%)
		TM helix 3	135..165	CDD:320452	17/29 (59%)
		TM helix 4	177..199	CDD:320452	5/21 (24%)
		TM helix 5	216..245	CDD:320452	12/41 (29%)
		TM helix 6	301..331	CDD:320452	12/29 (41%)
		TM helix 7	344..369	CDD:320452	11/24 (46%)