DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dop1R1 and htr4

DIOPT Version :9

Sequence 1:NP_001262563.1 Gene:Dop1R1 / 41726 FlyBaseID:FBgn0011582 Length:560 Species:Drosophila melanogaster
Sequence 2:XP_002939852.1 Gene:htr4 / 100493952 XenbaseID:XB-GENE-993770 Length:386 Species:Xenopus tropicalis


Alignment Length:356 Identity:119/356 - (33%)
Similarity:176/356 - (49%) Gaps:54/356 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 EPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRI-GNLFLASLAIADLFVASLVMTF 184
            |...:.:.:|:..|:|.:|.:::.||:||.:|:..:|.||:| .|.|:.|||.|||.|:.|||.|
 Frog    11 EGYGVAARIVLISFISAVILMTILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPF 75

  Fly   185 AGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHI-KDPLRYGRWVTRRVAVIT 248
            ..:..:...||:|..||....:.||:.:|||||:||.||:|||..| ..||.|...:|.....:.
 Frog    76 GAIELVQEKWIYGEMFCLVRTSLDVLLTTASILHLCCISLDRYYAICCQPLVYRNKMTPLRITLM 140

  Fly   249 IAAIWLLAAFVSFVPI-----SLGIHRPDQPLIFEDNGKKY------PTCALDLTPTYAVVSSCI 302
            ::..|::..|:||:||     |:||    ..||   ..:||      ..|...:...||:..|.:
 Frog   141 LSGCWIIPTFISFLPIMQGWNSIGI----LDLI---ETRKYNKSSNSTNCIFMVNKPYAITCSVV 198

  Fly   303 SFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSS 367
            :||.|..:|:..|.|:|..|::|.:.|..:.|.|..|:                      |.|..
 Frog   199 AFYIPFFLMVLAYYRIYITAREHARQIGVLQRAGAPAD----------------------HRHQH 241

  Fly   368 PYHVSDH------KAAVTVGVIMGVFLICWVPFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAF 426
            |...:.|      |||.|:.:|||.|.:||.|||..|:...|....:..:.:....||||.||..
 Frog   242 PDQHTTHRMKTETKAAKTLCIIMGCFCLCWAPFFITNVVDPFINYSVPVELWTAFLWLGYINSGL 306

  Fly   427 NPIIYSIFNKEFRDAFKRILTMRNPWCCAQD 457
            ||.:|:..||.||.||..||      ||..:
 Frog   307 NPFLYAFLNKSFRRAFLIIL------CCGDE 331

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dop1R1NP_001262563.1 7tm_4 134..>266 CDD:304433 55/138 (40%)
7tm_1 145..431 CDD:278431 103/304 (34%)
htr4XP_002939852.1 7tmA_5-HT4 19..322 CDD:320184 112/331 (34%)
TM helix 1 20..46 CDD:320184 9/25 (36%)
TM helix 2 54..80 CDD:320184 13/25 (52%)
TM helix 3 92..122 CDD:320184 15/29 (52%)
TM helix 4 135..158 CDD:320184 6/22 (27%)
TM helix 5 188..217 CDD:320184 10/28 (36%)
TM helix 6 251..281 CDD:320184 14/29 (48%)
TM helix 7 290..315 CDD:320184 9/24 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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