DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dop1R1 and adrb2

DIOPT Version :9

Sequence 1:NP_001262563.1 Gene:Dop1R1 / 41726 FlyBaseID:FBgn0011582 Length:560 Species:Drosophila melanogaster
Sequence 2:NP_001116897.2 Gene:adrb2 / 100144654 XenbaseID:XB-GENE-494302 Length:419 Species:Xenopus tropicalis


Alignment Length:380 Identity:131/380 - (34%)
Similarity:205/380 - (53%) Gaps:35/380 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 YDGTTLTSFY-NESSWTNASEMDTIVGEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYT 155
            |..:||.... |.|:.:|||       ::|....:|.   :||.:|.::.:.|.||:||..||..
 Frog    10 YPNSTLEQLVSNVSNTSNAS-------DKPGDAWMVG---MGIIMSCIVLVIVLGNVLVITAIAK 64

  Fly   156 ERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLC 220
            .:.|:.:.|.|:.|||.|||.:..:|:.|...:.:|..|:|...:|:.|.:.|::|.||||..||
 Frog    65 FQRLQTVTNYFITSLACADLLMGLIVVPFGASSIILDTWVFNNFWCEFWTSVDILCVTASIETLC 129

  Fly   221 AISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPL---IFEDNGK 282
            .|::|||..|..|.||...:|:..|.|.|..:|:::...||:||.:..:|.::..   .::|   
 Frog   130 VIAVDRYFAITSPFRYQSLLTKCKARIVILLVWVVSTLTSFLPIYMHWYRIEEESALHCYDD--- 191

  Fly   283 KYPTCALDLT-PTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKS 346
              |:|....| |.||:.||.||||.|.||||.:|.|::..|:|.:|.|          :|...:.
 Frog   192 --PSCCFFFTNPAYAISSSIISFYLPLVVMIFVYARVFQEAKKQLKKI----------DKSEGRF 244

  Fly   347 IRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCKTCIGGQ 411
            ..:...|....|..|..|  |.:.:.:|||..|:|:|||.|.:||:|||.|||.....|..|..:
 Frog   245 HNQNNQQDTNGKQGNKRT--SKFWLKEHKALKTLGIIMGTFTLCWLPFFIVNIVQVMHKDFIPVK 307

  Fly   412 TFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMRNPWCCAQDVGNIHPRNS 466
            .:..|.|:||.||||||:|| ..:.:||..|:.:|.:|.|.  ::...|.:|:::
 Frog   308 VYNFLNWVGYVNSAFNPLIY-CRSPDFRYTFQELLCLRKPG--SKAYANGYPQSN 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dop1R1NP_001262563.1 7tm_4 134..>266 CDD:304433 49/131 (37%)
7tm_1 145..431 CDD:278431 107/289 (37%)
adrb2NP_001116897.2 7tmA_Beta2_AR 38..337 CDD:341355 116/319 (36%)
TM helix 1 39..65 CDD:341355 10/28 (36%)
TM helix 2 72..99 CDD:341355 10/26 (38%)
TM helix 3 110..140 CDD:341355 14/29 (48%)
TM helix 4 152..175 CDD:341355 8/22 (36%)
TM helix 5 200..232 CDD:341355 17/31 (55%)
TM helix 6 267..297 CDD:341355 17/29 (59%)
TM helix 7 306..331 CDD:341355 12/25 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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