DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dop1R1 and adrb2b

DIOPT Version :9

Sequence 1:NP_001262563.1 Gene:Dop1R1 / 41726 FlyBaseID:FBgn0011582 Length:560 Species:Drosophila melanogaster
Sequence 2:NP_001082940.2 Gene:adrb2b / 100037315 ZFINID:ZDB-GENE-070410-32 Length:409 Species:Danio rerio


Alignment Length:381 Identity:142/381 - (37%)
Similarity:206/381 - (54%) Gaps:47/381 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 IEIDIQLLTNGYDGTTLTSFY-NESSWTNASEMDTIVGEEPEPLSL-------VSIVVVGIFLSV 137
            :|.|..|:|..      ||.| |.|:..|||          .|:||       ..:|::.|.:.:
Zfish     1 MEGDNTLITEN------TSLYMNISAGLNAS----------SPVSLSVSEYSDAEVVLISILIGI 49

  Fly   138 LIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCD 202
            |:.:.|.||.||..||...:.|:.:.|.|::|||.|||.:..:|:.|.....||..|.||..||:
Zfish    50 LVLVIVFGNALVISAIVRFQRLQTVTNYFISSLACADLVMGLMVVPFGACYILLNTWHFGNFFCE 114

  Fly   203 TWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLG 267
            .|.|.||:|.||||..||.|::||||.|..||||...:|:|.|...:..:|.:||.:||:||.:.
Zfish   115 FWTATDVLCVTASIETLCVIALDRYIAIMWPLRYQSMLTKRKACGMVIGVWAVAALISFLPIHME 179

  Fly   268 IHRPDQP---LIFEDNGKKYPTCA-LDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKS 328
            ....|:|   ...|:     |||. .:....|||.||.||||.|.|:|..:|.|::..|::.::.
Zfish   180 WWVSDEPEALSCLEE-----PTCCDFNTNAAYAVTSSIISFYIPLVIMAFVYSRVFQEARRQLQK 239

  Fly   329 IKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVP 393
            |..:  .|.:    |.:|:...:..    :::|..|   .:.:.||||..|:|:|||.|.:||:|
Zfish   240 IDRI--EGRI----RTQSLSTQEGN----EIKNRRT---KFCMKDHKALKTLGIIMGTFTLCWLP 291

  Fly   394 FFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMR 449
            ||.:|:.||..|.......|:||.|:||:||||||:|| ..:.|||.||:.||..|
Zfish   292 FFVLNVVAAIWKMDNIMLPFRILNWIGYANSAFNPLIY-CRSPEFRCAFQEILCWR 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dop1R1NP_001262563.1 7tm_4 134..>266 CDD:304433 57/131 (44%)
7tm_1 145..431 CDD:278431 113/289 (39%)
adrb2bNP_001082940.2 7tm_GPCRs 41..339 CDD:333717 122/316 (39%)
TM helix 1 43..67 CDD:320095 9/23 (39%)
TM helix 2 76..98 CDD:320095 10/21 (48%)
TM helix 3 114..136 CDD:320095 12/21 (57%)
TM helix 4 159..175 CDD:320095 5/15 (33%)
TM helix 5 204..227 CDD:320095 12/22 (55%)
TM helix 6 272..297 CDD:320095 14/24 (58%)
TM helix 7 308..333 CDD:320095 14/25 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.