DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3199 and KRT32

DIOPT Version :9

Sequence 1:	NP_650342.2	Gene:	CG3199 / 41725	FlyBaseID:	FBgn0038210	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_002269.3	Gene:	KRT32 / 3882	HGNCID:	6449	Length:	448	Species:	Homo sapiens

Alignment Length:	154	Identity:	34/154 - (22%)
Similarity:	52/154 - (33%)	Gaps:	55/154 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 NVSEFKPNASHTFQAEPPNLAQTVEENGIDFEVVYDEQVVGLG-------------KLSLPKR-- 130
            |..|.:..|.|:.:   .:|..|:.|:    |..|..|:..:.             :..|.::
Human   320 NTLEIELQAQHSLR---DSLENTLTES----EARYSSQLAQMQCMITNVEAQLAEIRADLERQNQ 377

  Fly   131 -----LSTRIKLDMKAFSYTSTCPLEMEGKPVGALEFLCKLFIKCGDYAREG-ETC---PNLDRN 186
                 |..|.:|:.:..:|.|.  ||.|.         |||  .|...:... .||   |.:.|.
Human   378 EYQVLLDVRARLEGEINTYRSL--LENED---------CKL--PCNPCSTPSCTTCVPSPCVPRT 429

  Fly   187 LS-PRDIVFVVGKSQANTSCCDPC 209
            :. ||    .||..      |.||
Human   430 VCVPR----TVGMP------CSPC 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3199	NP_650342.2	DUF4788	45..>216	CDD:292651	34/154 (22%)
KRT32	NP_002269.3	Head	1..96
		Filament	95..406	CDD:278467	19/103 (18%)
		Coil 1A	97..131
		Uso1_p115_C	112..230	CDD:282695
		Linker 1	132..142
		Coil 1B	143..243
		Linker 12	244..259
		Coil 2	260..403		18/91 (20%)
		Prefoldin	275..>355	CDD:298833	10/41 (24%)
		Tail	404..448		15/61 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900