DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3199 and Krt2

DIOPT Version :9

Sequence 1:	NP_650342.2	Gene:	CG3199 / 41725	FlyBaseID:	FBgn0038210	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_034798.2	Gene:	Krt2 / 16681	MGIID:	96699	Length:	707	Species:	Mus musculus

Alignment Length:	89	Identity:	20/89 - (22%)
Similarity:	34/89 - (38%)	Gaps:	33/89 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LEVKGVVLADARKLLVKVKFGG--NNLS----------------LTASRTNVSEFKPNASHTFQA 95
            ||.:..||....:||.::..|.  .||.                |:|.||:.           ::
Mouse   220 LEQQNQVLRTKWELLQQLDVGSRTTNLDPIFQAYIGMLKKQVDRLSAERTSQ-----------ES 273

  Fly    96 EPPNLAQTVEENGIDFEVVYDEQV 119
            |..|:...||    ||:..|::::
Mouse   274 ELNNMQDLVE----DFKKKYEDEI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3199	NP_650342.2	DUF4788	45..>216	CDD:292651	20/89 (22%)
Krt2	NP_034798.2	Head. /evidence=ECO:0000255	1..198
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Keratin_2_head	29..>80	CDD:292825
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..59
		Filament	198..511	CDD:278467	20/89 (22%)
		Coil 1A. /evidence=ECO:0000255	199..234		4/13 (31%)
		Linker 1. /evidence=ECO:0000255	235..253		3/17 (18%)
		Coil 1B. /evidence=ECO:0000255	254..345		11/55 (20%)
		Linker 12. /evidence=ECO:0000255	346..369
		Coil 2. /evidence=ECO:0000255	370..508
		Tail. /evidence=ECO:0000255	509..707
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	531..707
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900