DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3199 and Krt32

DIOPT Version :9

Sequence 1:	NP_650342.2	Gene:	CG3199 / 41725	FlyBaseID:	FBgn0038210	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001152846.2	Gene:	Krt32 / 16670	MGIID:	1309995	Length:	453	Species:	Mus musculus

Alignment Length:	217	Identity:	42/217 - (19%)
Similarity:	76/217 - (35%)	Gaps:	60/217 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TRLEVKGVVLADA---RKLLVKVKFGGNNLSLTASRTNVSE----FKPNASH------------- 91
            |.|.::.:|.||.   |::|.::..  |...|.|...::.|    .|.|...
Mouse   192 TELALRQLVEADTNGLRRILDELTL--NKADLEAQVESLKEELLCLKRNHEEEVGVLRQQLGDRL 254

  Fly    92 --TFQAEPP-NLAQTVEENGIDFEVVYD------EQVVGLGKLSLPKRLSTRIK---------LD 138
              ...|.|| :|.:.:||....:|.:.:      |:...:....|.|:::|..:         :|
Mouse   255 NIEVDAAPPVDLTRMLEEMRCQYETMVETNHRDVEEWFNMQMEELNKQVATSSEQLQSYQSDIID 319

  Fly   139 MKAFSYTSTCPLEMEGKPVGALEFLCKLFIKCGDYAREGETCPNLDRNLSPRDIVFVVGKSQANT 203
            ::....|....|:.:.....:||...            |||.......||....:....:||.:.
Mouse   320 LRRTVNTLEIELQAQHSLRDSLENTL------------GETEGRFTSQLSQMQCMITNVESQLSD 372

  Fly   204 SCCDPCRDALEIEARKQKDYSI 225
            ..||     ||   |:.::|.:
Mouse   373 IRCD-----LE---RQNQEYKV 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3199	NP_650342.2	DUF4788	45..>216	CDD:292651	40/206 (19%)
Krt32	NP_001152846.2	PMG	1..>92	CDD:283053
		Filament	100..411	CDD:278467	42/217 (19%)
		DUF4795	102..>256	CDD:292662	13/65 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900