DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3199 and KRT28

DIOPT Version :9

Sequence 1:	NP_650342.2	Gene:	CG3199 / 41725	FlyBaseID:	FBgn0038210	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_853513.2	Gene:	KRT28 / 162605	HGNCID:	30842	Length:	464	Species:	Homo sapiens

Alignment Length:	54	Identity:	14/54 - (25%)
Similarity:	21/54 - (38%)	Gaps:	18/54 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KGKDKGKKGKKSVFRAKSTVVPTAPPEPVFDRNLPVFSFDLVITRLEVKGVVLA 57
            ||...|..|..|...:|:|:|.|                  |:..|:.:|.||:
Human   405 KGFGSGSPGNSSKDLSKTTLVKT------------------VVEELDQRGKVLS 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3199	NP_650342.2	DUF4788	45..>216	CDD:292651	5/13 (38%)
KRT28	NP_853513.2	Head. /evidence=ECO:0000255	1..85
		Filament	85..396	CDD:278467
		Coil 1A. /evidence=ECO:0000255	86..121
		Linker 1. /evidence=ECO:0000255	122..143
		Coil 1B. /evidence=ECO:0000255	144..235
		Linker 12. /evidence=ECO:0000255	236..258
		Coil 2. /evidence=ECO:0000255	259..397
		Tail. /evidence=ECO:0000255	398..464		14/54 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	443..464
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900