DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9722 and FAIM2

DIOPT Version :9

Sequence 1:	NP_650341.1	Gene:	CG9722 / 41724	FlyBaseID:	FBgn0038209	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_036438.2	Gene:	FAIM2 / 23017	HGNCID:	17067	Length:	316	Species:	Homo sapiens

Alignment Length:	255	Identity:	91/255 - (35%)
Similarity:	137/255 - (53%)	Gaps:	16/255 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IPLGRYTAYGSEIGQDDPDKG-----------LGFCSASIRRGFIRKVYLILLAQLITSLVVIVS 75
            :||....||.........|.|           ..:....:||.|:||||.|||.||:.:|.|:..
Human    59 VPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVAL 123

  Fly    76 LTADKRVRLMVAESTWIFVVAILIVVFSLVALGCNEDLRRQTPANFIFLSAFTIAESFLLGVAAC 140
            .|....|:..|..:...:..:..:...:.:.|.|....||..|.|.|.|:.||::.::|.|:.:.
Human   124 FTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSS 188

  Fly   141 RYAPMEIFMAVLITASVCLGLTLFALQTRYDFTVMGGLLVSCLIILLFFG-IVTIFVGGHMVT-- 202
            .|....:.:.:.|||.|||.:|:|:.||::|||...|:|...|:.|.|.| |:.|.:....|.
Human   189 YYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWL 253

  Fly   203 -TIYASLSALLFSVYLVYDTQLMMGGKHRYSISPEEYIFAALNIYMDVMNIFLDILQLIG 261
             .:||:|.|.:|:::|..||||:||.: |:|:|||||||.|||||:|::.||...|||.|
Human   254 HAVYAALGAGVFTLFLALDTQLLMGNR-RHSLSPEEYIFGALNIYLDIIYIFTFFLQLFG 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9722	NP_650341.1	LFG_like	44..261	CDD:198410	84/220 (38%)
FAIM2	NP_036438.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53
FAIM2	NP_036438.2	LFG_like	92..312	CDD:198410	84/220 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm8436
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830