Protein Alignment RpII140 and polr3b

DIOPT Version :9

• Sequence 1: NP_001287323.1
• Gene: RpII140 / 41721
• FlyBaseID: FBgn0262955
• Length: 1176
• Species: Drosophila melanogaster
• Sequence 2: XP_021323450.1
• Gene: polr3b / 562329
• ZFINID: ZDB-GENE-030131-2887
• Length: 1130
• Species: Danio rerio
• Alignment Length: 1173
• Identity: 452/1173 - (38%)
• Similarity: 679/1173 - (57%)
• Gaps: 95/1173 - (8%)

  Fly    25 EACWIVINAYFDEKGLVRQQLDSFDEFIQMSVQRIVEDSPAIELQAEAQHTSGEVETPPRFSLKF 89
            |..|.::.|:...||||:|.:|||:.||.:.:::|::.:..|...|:           |.:.||:
Zfish    22 EEKWKLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKITSDAD-----------PMWYLKY 75

  Fly    90 EQIYLSKPTHWEKDGSPSPMMPNEARLRNLTYSAPLYVDITKTKN----VEGLDPVETQHQKTFI 150
            ..||:..|...|......|:.|:|.|||::|||||:.|||..|:.    :....|         |
Zfish    76 LNIYVGMPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALP---------I 131

  Fly   151 GKIPIMLRSTYCLLSQLTDRDLTELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFSMKDGK 215
            |::||||||:.|:|:..|..:.::|||||||||||||:.|.|||::.||:::.|.:.|...:.|.
Zfish   132 GRMPIMLRSSNCVLTGKTPMEFSKLNECPLDPGGYFIVKGQEKVILIQEQLSKNRIIVDQDRKGT 196

  Fly   216 YAFKTEIRSCLEHSSRPTSTLWVNMMAR-GSQNIKKSAIGQRIIAILPYIKQEIPIMIVFRALGF 279
            .. .:...|..|..||      .||:.: |...:|.:.           :.::.||.|:|:|:|.
Zfish   197 VG-ASVTSSTHEKKSR------TNMIVKQGRFYLKHNT-----------LSEDAPIAIIFKAMGV 243

  Fly   280 VADRDILEHIIYDFDDPEMMEMVKPSLDEAFVVQ--EQNVALNFIGARGARP---GVTKDKRIKY 339
            .:|::|::.|   ..:..:|....|||:|....|  .|..||.:||.:..|.   |..|..:::.
Zfish   244 ESDQEIVQMI---GTEEHVMAAFAPSLEECQKAQIFTQTQALRYIGNKVRRQRMWGGPKKTKMEE 305

  Fly   340 AKEILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRRELDDRDHYGNKRLDLAGPLLAFL 404
            |:|:|...:|.||.|.:|....|..:|..||.|::||. |..::||||:||||||:|||.||:.|
Zfish   306 ARELLASTILTHVPVKEFNFRAKCIYLAVMVRRVILAQ-GDNKVDDRDYYGNKRLELAGQLLSLL 369

  Fly   405 FRGLFKNLMKEVRMYTQKFI--DRGKDFNLELAIKTNIITDGLRYSLATGNWGDQKKAHQARAGV 467
            |..|||....|::....:.|  .|...|::...::.:.||:|:..:::|||| ..|:....|.||
Zfish   370 FEDLFKKFNSELKKIADQIIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNW-SLKRFKMDRQGV 433

  Fly   468 SQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMLCPAETPEGAAVGLVKNLALMAY 532
            :|||:||:|.|.|..:.|::|...:..|::.||.|..:.||||||::||||.|.|||||||||.:
Zfish   434 TQVLSRLSFISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTH 498

  Fly   533 ISVGSQPSPILEFLEEWSMENLEEIAPSAIADAT--KIFVNGCWVGIHRDPEQLMATLRKLRRQM 595
            |:...:..||::......:|::..:....::..|  .:|:||..:|:.||.::|:.|.|.:|| .
Zfish   499 ITTDMEDGPIIKLAFNLGVEDVNLLCGEELSYPTVFLVFLNGNILGVIRDHQKLVYTFRLMRR-A 562

  Fly   596 DIIVSEVSMIRDIRDREIRIYTDAGRICRPLLIVENGSLLLKKTHVEMLKE--RDYNNYSWQVLV 658
            ..|...||:..::.||.:.|.:|.||:|||.:||:||...:|..|:|.|.:  |.:.::     :
Zfish   563 GFINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKNGKPAVKNKHIEELSQGYRTFEDF-----L 622

  Fly   659 ASGVVEYIDTLEEETVMIAMSPYDLKQDKDYAYCTTYTHCEIHPAMILGVCASIIPFPDHNQSPR 723
            ...:|||:|..||....||:..:.:.:|.        ||.||.|..:|||||.:||:|.||||||
Zfish   623 HESLVEYLDVNEENDCNIALYEHMISKDT--------THLEIEPFTLLGVCAGLIPYPHHNQSPR 679

  Fly   724 NTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVTTRSMEYLRFRELPAGINSIVAILCYT 788
            ||||.||||||||....|...|:|||.::|.||.:|:|.|:::|.:.|.:||||.|:.||::.|:
Zfish   680 NTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQRPMVKTKTIELIDFEKLPAGQNATVAVMSYS 744

  Fly   789 GYNQEDSVILNASAVERGFFRSVFYRSYKDSENKRVGDQEENFEKPHRGTCQGMRNAHYDK---- 849
            ||:.||:::||.::::|||.|.:.|::.|.:..:..   .:.|:|    ....|.:|...|
Zfish   745 GYDIEDALVLNKASLDRGFGRCLVYKNAKCTLRRYT---NQTFDK----VMGPMLDAETRKPIWR 802

  Fly   850 ---LDDDGIIAPGIRVSGDDVVIGKTI-TLPENDDELDSNTKRFSKRDASTFLRNSETGIVDQVM 910
               ||.|||.:||.:|....|::.|:: |:.:...|..:...:...|:.....:.:....:::||
Zfish   803 HSILDADGICSPGEKVENKQVLVNKSMPTVTQTPLEGSAQPGQPQYREVPVSYKGATDSYIEKVM 867

  Fly   911 LTLNSEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMAFTCEGLAPDIIINPHAIP 975
            ::.|:|.....||.:|..|.|:|||||:|||||||.||:...||||.|...|:.||||:|||..|
Zfish   868 ISSNAEDAFLVKILLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGYP 932

  Fly   976 SRMTIGHLIECLQGKLGSNKGEIGDATPFNDAVNVQKISTFLQEYGYHLRGNEVMYNGHTGRKIN 1040
            ||||:|.|||.|.||.|...|.....|.|..: .|:.:...|..|||:.:|.:.:.:|.||..:.
Zfish   933 SRMTVGKLIELLAGKAGVLDGRFHYGTAFGGS-KVKDVCEDLIRYGYNYQGKDYVTSGITGEPLE 996

  Fly  1041 AQVFLGPTYYQRLKHMVDDKIHSRARGPVQILVRQPMEGRARDGGLRFGEMERDCQISHGAAQFL 1105
            |.::.||.|||:|||||.||:|:|||||..:|.|||.|||:||||||.|||||||.|.:||:..|
Zfish   997 AYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLL 1061

  Fly  1106 RERLFEVSDPYRVHICNFCGLIAIANLRNNTFECKGCKNKTQISQVRLPYAAKLLFQELMSMNIA 1170
            .|||...||.:.|.:|..|||:..:..      |..||:...:|.:|:|||.|||||||.||||.
Zfish  1062 LERLMISSDAFEVDVCGQCGLLGYSGW------CHYCKSSCHVSSLRIPYACKLLFQELQSMNII 1120

  Fly  1171 PRL 1173
            |||
Zfish  1121 PRL 1123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpII140	NP_001287323.1	PRK08565	28..1176	CDD:236291	451/1170 (39%)
polr3b	XP_021323450.1	RNA_pol_B_RPB2	37..1124	CDD:238353	447/1158 (39%)
		RNA_pol_Rpb2_4	536..597	CDD:309626	24/61 (39%)
		RNA_pol_Rpb2_5	618..658	CDD:309627	13/52 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0085
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100190
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X610
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720