Protein Alignment RpII140 and rpb-2

DIOPT Version :9

• Sequence 1: NP_001287323.1
• Gene: RpII140 / 41721
• FlyBaseID: FBgn0262955
• Length: 1176
• Species: Drosophila melanogaster
• Sequence 2: NP_498047.2
• Gene: rpb-2 / 175668
• WormBaseID: WBGene00016140
• Length: 1194
• Species: Caenorhabditis elegans
• Alignment Length: 1186
• Identity: 933/1186 - (78%)
• Similarity: 1053/1186 - (88%)
• Gaps: 17/1186 - (1%)

  Fly     1 MMYDNEEELYEE-------ENAEEISHELWQEACWIVINAYFDEKGLVRQQLDSFDEFIQMSVQR 58
            ||||:|:|:..:       ::::|||.|.||||||:||:|||||||||||||||||||:||:|||
 Worm     1 MMYDDEDEMVNDPMDGDYIDDSDEISAEAWQEACWVVISAYFDEKGLVRQQLDSFDEFVQMNVQR 65

  Fly    59 IVEDSPAIELQAEAQHTSGEVETPPRFSLKFEQIYLSKPTHWEKDGSPSPMMPNEARLRNLTYSA 123
            ||||||.:|||:|.||...::|.|.:|||||.||||||||||||||:|.||||||||||||||::
 Worm    66 IVEDSPPVELQSENQHLGTDMENPAKFSLKFNQIYLSKPTHWEKDGAPMPMMPNEARLRNLTYAS 130

  Fly   124 PLYVDITK--TKNVEGLDPVETQHQKTFIGKIPIMLRSTYCLLSQLTDRDLTELNECPLDPGGYF 186
            ||||||||  |::....:.|   :.|.|:||:|:||||:||:||.:|||||||||||||||||||
 Worm   131 PLYVDITKVVTRDDSATEKV---YDKVFVGKVPVMLRSSYCMLSNMTDRDLTELNECPLDPGGYF 192

  Fly   187 IINGSEKVLIAQEKMATNTVYVFSMKDGKYAFKTEIRSCLEHSSRPTSTLWVNMMARGSQNIKKS 251
            :||||||||||||||||||||||||||||||||||.|||||:|||||||:||||:|||....||:
 Worm   193 VINGSEKVLIAQEKMATNTVYVFSMKDGKYAFKTECRSCLENSSRPTSTMWVNMLARGGGGGKKT 257

  Fly   252 AIGQRIIAILPYIKQEIPIMIVFRALGFVADRDILEHIIYDFDDPEMMEMVKPSLDEAFVVQEQN 316
            |:|||||.|||||||||||||||||||||:|||||.||||||:|||||||||||||||||:||||
 Worm   258 AMGQRIIGILPYIKQEIPIMIVFRALGFVSDRDILGHIIYDFNDPEMMEMVKPSLDEAFVIQEQN 322

  Fly   317 VALNFIGARGARPGVTKDKRIKYAKEILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRR 381
            |||||||||||:||||:::|||||:||||||:|||||||:.||||||:|:||||||||||:||||
 Worm   323 VALNFIGARGAKPGVTREQRIKYAREILQKELLPHVGVSEHCETKKAFFIGYMVHRLLLAALGRR 387

  Fly   382 ELDDRDHYGNKRLDLAGPLLAFLFRGLFKNLMKEVRMYTQKFIDRGKDFNLELAIKTNIITDGLR 446
            |||||||.|||||||||||||||||.||:||:||:||..||:|::..||.|::.:||:.||.||.
 Worm   388 ELDDRDHIGNKRLDLAGPLLAFLFRSLFRNLLKEMRMTAQKYINKNDDFALDVCVKTSTITRGLT 452

  Fly   447 YSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMLC 511
            ||||||||||||||||:||||||||||||:.:|||||||.||||||:||||||||||||.|||:|
 Worm   453 YSLATGNWGDQKKAHQSRAGVSQVLNRLTYTATLSHLRRANSPIGREGKLAKPRQLHNTQWGMVC 517

  Fly   512 PAETPEGAAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVG 576
            |||||||.||||||||||||||||||.|.||||||||||||||||::||||||||||||||.|||
 Worm   518 PAETPEGQAVGLVKNLALMAYISVGSLPEPILEFLEEWSMENLEEVSPSAIADATKIFVNGAWVG 582

  Fly   577 IHRDPEQLMATLRKLRRQMDIIVSEVSMIRDIRDREIRIYTDAGRICRPLLIVENGSLLLKKTHV 641
            |||:|:|||.||:|||||||||||||||:||||||||||||||||:|||||||||..|.|||.|:
 Worm   583 IHREPDQLMTTLKKLRRQMDIIVSEVSMVRDIRDREIRIYTDAGRVCRPLLIVENQKLALKKRHI 647

  Fly   642 EMLKER--DYNNYSWQVLVASGVVEYIDTLEEETVMIAMSPYDLKQDKDYAYCTTYTHCEIHPAM 704
            :.|||.  :.|.|:|..||..||||.||::||||.||||.|.||:..   .||.|:|||||||||
 Worm   648 DQLKEAADEANKYTWSDLVGGGVVELIDSMEEETSMIAMMPEDLRSG---GYCDTHTHCEIHPAM 709

  Fly   705 ILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVTTRSMEYL 769
            ||||||||||||||||||||||||||||||||||.|||||||||||||||||.||||||||||||
 Worm   710 ILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYTTNFHVRMDTLAHVLYYPQKPLVTTRSMEYL 774

  Fly   770 RFRELPAGINSIVAILCYTGYNQEDSVILNASAVERGFFRSVFYRSYKDSENKRVGDQEENFEKP 834
            ||.|||||||:|||||.|:|||||||||:|.||::||.|||||||||:|:|.......||..|||
 Worm   775 RFNELPAGINAIVAILSYSGYNQEDSVIMNNSAIDRGLFRSVFYRSYRDNEANLDNANEELIEKP 839

  Fly   835 HRGTCQGMRNAHYDKLDDDGIIAPGIRVSGDDVVIGKTITLPENDDELDSNTKRFSKRDASTFLR 899
            .|..|.|||::.|||||:||||:||:|||||||:||||:.||:.||:||::.|::.|||||||||
 Worm   840 TREKCSGMRHSLYDKLDEDGIISPGMRVSGDDVIIGKTVALPDIDDDLDASGKKYPKRDASTFLR 904

  Fly   900 NSETGIVDQVMLTLNSEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMAFTCEGLA 964
            :|||||||||||:|||:|.||.|||:||||:||||||||||||||||.||.||||||.||.|||.
 Worm   905 SSETGIVDQVMLSLNSDGNKFVKIRMRSVRLPQIGDKFASRHGQKGTMGIMYRQEDMPFTAEGLT 969

  Fly   965 PDIIINPHAIPSRMTIGHLIECLQGKLGSNKGEIGDATPFNDAVNVQKISTFLQEYGYHLRGNEV 1029
            |||||||||:|||||||||||||||||.:|||||||||||||.|||||||..|.|||||||||||
 Worm   970 PDIIINPHAVPSRMTIGHLIECLQGKLSANKGEIGDATPFNDTVNVQKISGLLCEYGYHLRGNEV 1034

  Fly  1030 MYNGHTGRKINAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILVRQPMEGRARDGGLRFGEMERD 1094
            |||||||:|:..|:|.|||||||||||||||||||||||:|::.|||||||||||||||||||||
 Worm  1035 MYNGHTGKKLTTQIFFGPTYYQRLKHMVDDKIHSRARGPIQMMNRQPMEGRARDGGLRFGEMERD 1099

  Fly  1095 CQISHGAAQFLRERLFEVSDPYRVHICNFCGLIAIANLRNNTFECKGCKNKTQISQVRLPYAAKL 1159
            |||||||.||||||||||||||.|::||.||||.:||||.|:||||.|:||||:|.||:|||.||
 Worm  1100 CQISHGATQFLRERLFEVSDPYHVYVCNNCGLIVVANLRTNSFECKACRNKTQVSAVRIPYACKL 1164

  Fly  1160 LFQELMSMNIAPRLMV 1175
            ||||||||:|||||||
 Worm  1165 LFQELMSMSIAPRLMV 1180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpII140	NP_001287323.1	PRK08565	28..1176	CDD:236291	918/1152 (80%)
rpb-2	NP_498047.2	PRK08565	35..1183	CDD:236291	918/1152 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159258
Domainoid	1	1.000	654	1.000	Domainoid score	I69
eggNOG	1	0.900	-	-		E1_COG0085
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H722
Inparanoid	1	1.050	1905	1.000	Inparanoid score	I21
Isobase	1	0.950	-	0	Normalized mean entropy	S153
OMA	1	1.010	-	-		QHG62192
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	1	1.000	-	-		oto18750
orthoMCL	1	0.900	-	-		OOG6_100190
Panther	1	1.100	-	-	LDO	PTHR20856
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1184
SonicParanoid	1	1.000	-	-		X610
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790