Protein Alignment RpII140 and rpoa-2

DIOPT Version :9

• Sequence 1: NP_001287323.1
• Gene: RpII140 / 41721
• FlyBaseID: FBgn0262955
• Length: 1176
• Species: Drosophila melanogaster
• Sequence 2: NP_492476.1
• Gene: rpoa-2 / 172752
• WormBaseID: WBGene00008781
• Length: 1127
• Species: Caenorhabditis elegans
• Alignment Length: 1234
• Identity: 355/1234 - (28%)
• Similarity: 559/1234 - (45%)
• Gaps: 232/1234 - (18%)

  Fly    45 LDSFDEFIQMSVQRIVEDSPAIELQAEAQHTSGEVETPPRFSLKFEQIYLSKP---THWEKDGSP 106
            :||||..:....|...:..||.:.:.:    :|:..|     :||....|.||   |..:.....
 Worm    10 VDSFDFLVSKGCQFAAQAVPAEKFRLK----NGDAVT-----MKFTSAQLHKPTLDTGAKLTSDT 65

  Fly   107 SPMMPNEARLRNLTYSAPLYVDITKTKNVEGLDPVETQHQKTFIGKIPIMLRSTYCLLSQLTDRD 171
            .|::|.|.|.|.|||:..|.|.|....|...||.:|     ..:||:||||||..|.|..::.::
 Worm    66 LPLLPAECRQRGLTYAGNLKVGIDVHVNGSRLDIIE-----IILGKVPIMLRSEGCHLRGMSRKE 125

  Fly   172 LTELNECPLDPGGYFIINGSEKV---LIAQEKMATNTVYVFSMKD-GKY--AFKTEIRSCLEHSS 230
            |....|.|::.|||||:||||||   |||..:.....:...:.|: ||.  .|...:||..|:.:
 Worm   126 LVVAGEEPIEKGGYFIVNGSEKVIRLLIANRRNFPIAIIRKTFKEKGKLFSEFGVMMRSVKENHT 190

  Fly   231 RPTSTLWVNMMARGSQNIKKSAIGQRIIAILPYIKQEI---PIMIVFRAL----------GFVAD 282
            ....||  :.:..|:..:...            .::||   |:|.:.:||          ||...
 Worm   191 AVMMTL--HYLDTGTMQLALQ------------FRREIFYVPLMYIVKALTDKNDAVISAGFKRG 241

  Fly   283 RDILEHIIYDFDDPEMMEMVKPSLDEAFVVQEQNVALNFIGARGARPGVTK-----DKRIKYAKE 342
            |:..:     |....::.|:....:|..:.||  .|:..||:| .|..|:.     :..::..:.
 Worm   242 RNQDQ-----FYSSCILNMLAQCQEEEILNQE--AAIRAIGSR-FRVAVSDRVAPWEDDLEAGRF 298

  Fly   343 ILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRRELDDRDHYGNKRLDLAGPLLAFLFRG 407
            |:::.:|.|:.    .:.:|.:.|.||..:|:....|....:..|:...:...::|.:|..:.|.
 Worm   299 IIRECVLIHLD----SDEEKFHTLAYMTQKLIALVKGECAPETPDNPQFQEASVSGHILLLILRE 359

  Fly   408 LFKNLMKEVRMYTQKFIDRGKDFNLELA--IKT------NIITDGLRYSLATGNWGDQ-KKAHQA 463
            ..:|::..||...: ::...|||.|..|  :|.      ..||.|:.|.|||||...: ..|.|.
 Worm   360 RMENIIGMVRRKLE-YMSSRKDFILTSAAILKALGNHTGGEITRGMAYFLATGNLVTRVGLALQQ 423

  Fly   464 RAGVSQVLNRLTFASTLSHLRRVN-SPIGRDGKLAKPRQLHNTLWGMLCPAETPEGAAVGLVKNL 527
            .:|.|.:..|:.....:||.|.:: .....:.:....|:|....||.:||..||:||..||:.::
 Worm   424 ESGFSVIAERINQLRFVSHFRAIHRGAFFMEMRTTDVRKLRPEAWGFICPVHTPDGAPCGLLNHV 488

  Fly   528 A----LMAYISVGSQPSPILEFLEEWSMENL------EEIAPSAIADATKIFVNGCWVGIHRDPE 582
            .    ::..:|..|....:|..|..::.:.:      ||:.|        :.:||.::|.  .|.
 Worm   489 TASCRIVTDLSDNSNVPSLLAELGMYTHKTVALAPPGEELYP--------VLMNGRFLGY--VPI 543

  Fly   583 QLMATLRKLRRQMDI-------IVSEVSMIR---DIRDRE-----IRIYTDAGRICRPLLIVENG 632
            ...|::.:..|...:       ..||::::|   ||::.:     |.|.:||||:.||   |.|
 Worm   544 TKAASIERYLRCAKVAKDARIPYTSEIALVRRSTDIKNIQTQYPGIYILSDAGRLIRP---VRN- 604

  Fly   633 SLLLKKTHVEMLKERDYNNYSWQVLVASGVVEYIDTLEEETVMIAMSPYDLKQDKDYAYCTTYTH 697
                                     :|...||:|.|.|:..:.:.:.|.:.:..       ...|
 Worm   605 -------------------------LAMDAVEHIGTFEQVYLSVVLDPEEAEPG-------VTMH 637

  Fly   698 CEIHPAMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVT 762
            .|:||:.:.....::||||||||||||.||..||||.||..:..:|.|.|...:.|.:|.:|::.
 Worm   638 QELHPSCLFSFAGNLIPFPDHNQSPRNVYQCQMGKQTMGTAVHAWHSRADNKMYRLQFPQQPMLK 702

  Fly   763 TRSMEYLRFRELPAGINSIVAILCYTGYNQEDSVILNASAVERGFF------------------R 809
            ..:.|.....|.|.|.|:.||::.||||:.||::.:|.::.:|||.                  :
 Worm   703 LEAYEKYEMDEYPLGTNACVAVISYTGYDMEDAMTINKASYQRGFAHGTVIKVERINLVTERERK 767

  Fly   810 SVFYRSYKDSENKRVGDQEENFEKPHRGTCQGMRNAHYDKLDDDGIIAPGIRVSGDDVVIGKTIT 874
            ::|||:.:: |.|.||                          .||:..||.|...|:|..   :|
 Worm   768 TIFYRNPRE-EIKTVG--------------------------PDGLPIPGRRYFLDEVYY---VT 802

  Fly   875 LPENDDELDSNTKRFSKRDASTFLRNSETGIVDQVMLTLNSEGYKFCKIRVRSVRIPQIGDKFAS 939
            .  |.:..|..|.:|.      :...:..|:|..|.......|.|...|:.|..|.|.|||||||
 Worm   803 F--NMETGDFRTHKFH------YAEPAYCGLVRIVEQGEGDSGAKHALIQWRIERNPIIGDKFAS 859

  Fly   940 RHGQKGTCGIQYRQEDMAFTCEGLAPDIIINPHAIPSRMTIGHLIECLQGKLGSNKGEIGDATPF 1004
            ||||||.....:..|.:.|:..|:.||||.|||..|||||||.:||.:.||..:..||..||:||
 Worm   860 RHGQKGINSFLWPVESLPFSETGMVPDIIFNPHGFPSRMTIGMMIESMAGKAAATHGENYDASPF 924

  Fly  1005 -----NDAVNVQKISTFLQEYGYHLRGNEVMYNGHTGRKINAQVFLGPTYYQRLKHMVDDKIHSR 1064
                 |.|:|  .....|.:.||:..|||..|:|..||::..|:|.|..|||||:||:.||...|
 Worm   925 VFNEDNTAIN--HFGELLTKAGYNYYGNETFYSGVDGRQMEMQIFFGIVYYQRLRHMIADKFQVR 987

  Fly  1065 ARGPVQILVRQPMEGRARDGGLRFGEMERDCQISHGAAQFLRERLFEVSDPYRVHICNFCG--LI 1127
            |.||:..:..||::||.:.||:||||||||..|:||.:..|::||...||....:.|..||  |.
 Worm   988 ATGPIDPITHQPVKGRKKGGGIRFGEMERDAIIAHGTSFVLQDRLLNCSDRDVAYACRRCGSLLS 1052

  Fly  1128 AIANLR------------------NNTFECKGCKNKTQISQVRLPYAAKLLFQELMSMNIAPRL 1173
            .:.:.|                  ..|..|:.|....|:..:::|...:.|..||.:||:..:|
 Worm  1053 VLMSSRAGSHLLKKKRKDDEPLDYTETQRCRTCDKDDQVFLLQVPRVFRYLTAELAAMNVKIKL 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpII140	NP_001287323.1	PRK08565	28..1176	CDD:236291	355/1234 (29%)
rpoa-2	NP_492476.1	RNA_pol_B_RPB2	5..1116	CDD:238353	354/1232 (29%)
		RpoB	9..1116	CDD:223163	354/1232 (29%)
		RNA_pol_Rpb2_2	<216..339	CDD:282427	27/134 (20%)
		RNA_pol_Rpa2_4	538..595	CDD:284335	11/58 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0085
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820