Protein Alignment RpII140 and polr2b

DIOPT Version :9

• Sequence 1: NP_001287323.1
• Gene: RpII140 / 41721
• FlyBaseID: FBgn0262955
• Length: 1176
• Species: Drosophila melanogaster
• Sequence 2: XP_002937598.2
• Gene: polr2b / 100380205
• XenbaseID: XB-GENE-1012874
• Length: 1174
• Species: Xenopus tropicalis
• Alignment Length: 1175
• Identity: 1008/1175 - (85%)
• Similarity: 1105/1175 - (94%)
• Gaps: 1/1175 - (0%)

  Fly     2 MYDNEEELYEEENAEEISHELWQEACWIVINAYFDEKGLVRQQLDSFDEFIQMSVQRIVEDSPAI 66
            |||.:|::..:|:.:||:.:||||||||||::|||||||||||||||||||||||||||||:|.|
 Frog     1 MYDADEDMQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPI 65

  Fly    67 ELQAEAQHTSGEVETPPRFSLKFEQIYLSKPTHWEKDGSPSPMMPNEARLRNLTYSAPLYVDITK 131
            :||||||||:||||.|||:.|||||||||||||||:||:||||||||||||||||||||||||||
 Frog    66 DLQAEAQHTTGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITK 130

  Fly   132 TKNVEGLDPVETQHQKTFIGKIPIMLRSTYCLLSQLTDRDLTELNECPLDPGGYFIINGSEKVLI 196
            |...||.:.::||||||||||||||||||||||:.||||||.|||||||||||||||||||||||
 Frog   131 TVVKEGEEQIQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLI 195

  Fly   197 AQEKMATNTVYVFSMKDGKYAFKTEIRSCLEHSSRPTSTLWVNMMARGSQNIKKSAIGQRIIAIL 261
            |||||||||||||:.||.|||:..|.|||||:||||||::||:|:|||.|..|||||||||:|.|
 Frog   196 AQEKMATNTVYVFAKKDSKYAYTAECRSCLENSSRPTSSIWVSMLARGGQGAKKSAIGQRIVATL 260

  Fly   262 PYIKQEIPIMIVFRALGFVADRDILEHIIYDFDDPEMMEMVKPSLDEAFVVQEQNVALNFIGARG 326
            ||||||:||:|||||||||:||||||||||||:|||||||||||||||||:|||||||||||:||
 Frog   261 PYIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRG 325

  Fly   327 ARPGVTKDKRIKYAKEILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRRELDDRDHYGN 391
            |:|||||:||||||||:|||||||||||||||||||||||||||||||||:||||||||||||||
 Frog   326 AKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGN 390

  Fly   392 KRLDLAGPLLAFLFRGLFKNLMKEVRMYTQKFIDRGKDFNLELAIKTNIITDGLRYSLATGNWGD 456
            ||||||||||||||||:||||:||||:|.||||||||||||||||||.||:|||:||||||||||
 Frog   391 KRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGD 455

  Fly   457 QKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMLCPAETPEGAAV 521
            |||||||||||||||||||||||||||||:|||||||||||||||||||||||:||||||||.||
 Frog   456 QKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAV 520

  Fly   522 GLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMA 586
            ||||||||||||||||||||||||||||||||||||:|:||||||||||||||||||:||||||.
 Frog   521 GLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMN 585

  Fly   587 TLRKLRRQMDIIVSEVSMIRDIRDREIRIYTDAGRICRPLLIVENGSLLLKKTHVEMLKERDYNN 651
            |||||||||||||||||||||||:||||||||||||||||||||...||||:.|::.||||:|||
 Frog   586 TLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKRRHIDQLKEREYNN 650

  Fly   652 YSWQVLVASGVVEYIDTLEEETVMIAMSPYDLKQDKDYAYCTTYTHCEIHPAMILGVCASIIPFP 716
            ||||.|||||||||||||||||||:||:|.|| |:|..|||:|||||||||:|||||||||||||
 Frog   651 YSWQDLVASGVVEYIDTLEEETVMLAMTPDDL-QEKGVAYCSTYTHCEIHPSMILGVCASIIPFP 714

  Fly   717 DHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVTTRSMEYLRFRELPAGINSI 781
            ||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||
 Frog   715 DHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSI 779

  Fly   782 VAILCYTGYNQEDSVILNASAVERGFFRSVFYRSYKDSENKRVGDQEENFEKPHRGTCQGMRNAH 846
            |||..|||||||||||:|.|||:|||||||||||||:.|:|:..||||.||||.|.||||||:|.
 Frog   780 VAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAI 844

  Fly   847 YDKLDDDGIIAPGIRVSGDDVVIGKTITLPENDDELDSNTKRFSKRDASTFLRNSETGIVDQVML 911
            ||||||||:||||:|||||||:||||:|||||:|||:|..:|::|||.|||||.||||||||||:
 Frog   845 YDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMV 909

  Fly   912 TLNSEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMAFTCEGLAPDIIINPHAIPS 976
            |||.|||||||||||||||||||||||||||||||||||||||||.|||||:.||||||||||||
 Frog   910 TLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPS 974

  Fly   977 RMTIGHLIECLQGKLGSNKGEIGDATPFNDAVNVQKISTFLQEYGYHLRGNEVMYNGHTGRKINA 1041
            |||:||||||||||:.:|||||||||||||||||||||..|.:||||||||||:|||.|||||.:
 Frog   975 RMTVGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITS 1039

  Fly  1042 QVFLGPTYYQRLKHMVDDKIHSRARGPVQILVRQPMEGRARDGGLRFGEMERDCQISHGAAQFLR 1106
            |:|:|||||||||||||||||||||||:|||.|||||||:||||||||||||||||:||||||||
 Frog  1040 QIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLR 1104

  Fly  1107 ERLFEVSDPYRVHICNFCGLIAIANLRNNTFECKGCKNKTQISQVRLPYAAKLLFQELMSMNIAP 1171
            |||||.||||:||:||.|||:||||.|.:|:||:||:||||||.||:|||.||||||||||:|||
 Frog  1105 ERLFEASDPYQVHVCNLCGLMAIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAP 1169

  Fly  1172 RLMVT 1176
            |:|.:
 Frog  1170 RMMTS 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpII140	NP_001287323.1	PRK08565	28..1176	CDD:236291	995/1147 (87%)
polr2b	XP_002937598.2	PRK08565	27..1172	CDD:236291	994/1145 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	715	1.000	Domainoid score	I117
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H722
Inparanoid	1	1.050	2060	1.000	Inparanoid score	I46
OMA	1	1.010	-	-		QHG62192
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	1	1.000	-	-		oto102385
Panther	1	1.100	-	-	LDO	PTHR20856
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1184
SonicParanoid	1	1.000	-	-		X610
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110