Protein Alignment RpII140 and polr2b

DIOPT Version :9

• Sequence 1: NP_001287323.1
• Gene: RpII140 / 41721
• FlyBaseID: FBgn0262955
• Length: 1176
• Species: Drosophila melanogaster
• Sequence 2: NP_001019632.2
• Gene: polr2b / 100149268
• ZFINID: ZDB-GENE-041008-1
• Length: 1174
• Species: Danio rerio
• Alignment Length: 1175
• Identity: 1007/1175 - (85%)
• Similarity: 1104/1175 - (93%)
• Gaps: 1/1175 - (0%)

  Fly     2 MYDNEEELYEEENAEEISHELWQEACWIVINAYFDEKGLVRQQLDSFDEFIQMSVQRIVEDSPAI 66
            |||.:|::..:|:.:||:.:||||||||||::|||||||||||||||||||||||||||||:|.|
Zfish     1 MYDQDEDIQYDEDDDEITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPI 65

  Fly    67 ELQAEAQHTSGEVETPPRFSLKFEQIYLSKPTHWEKDGSPSPMMPNEARLRNLTYSAPLYVDITK 131
            :|||||||||||||.|||:.|||||||||||||||:||:||||||||||||||||||||||||||
Zfish    66 DLQAEAQHTSGEVEEPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITK 130

  Fly   132 TKNVEGLDPVETQHQKTFIGKIPIMLRSTYCLLSQLTDRDLTELNECPLDPGGYFIINGSEKVLI 196
            |...:|.:..:|||||||||||||||||||||||.||||||.|||||||||||||||||||||||
Zfish   131 TIIKDGEEQQQTQHQKTFIGKIPIMLRSTYCLLSGLTDRDLCELNECPLDPGGYFIINGSEKVLI 195

  Fly   197 AQEKMATNTVYVFSMKDGKYAFKTEIRSCLEHSSRPTSTLWVNMMARGSQNIKKSAIGQRIIAIL 261
            |||||||||||||:.||.|||:..|.|||||:|||||||:||:|||||.|.:|||||||||::.|
Zfish   196 AQEKMATNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMMARGGQGVKKSAIGQRIVSTL 260

  Fly   262 PYIKQEIPIMIVFRALGFVADRDILEHIIYDFDDPEMMEMVKPSLDEAFVVQEQNVALNFIGARG 326
            |||:||:||:|||||||||:||||||||||||||||||||||||||||||:|||||||||||:||
Zfish   261 PYIRQEVPIIIVFRALGFVSDRDILEHIIYDFDDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRG 325

  Fly   327 ARPGVTKDKRIKYAKEILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRRELDDRDHYGN 391
            |:|||||::|||||||:||||:||||||||||||||||||||||||||||:||||||||||||||
Zfish   326 AKPGVTKERRIKYAKEVLQKEVLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGN 390

  Fly   392 KRLDLAGPLLAFLFRGLFKNLMKEVRMYTQKFIDRGKDFNLELAIKTNIITDGLRYSLATGNWGD 456
            ||||||||||||||||:||||:||:|:|.||||||||||||||||||.||:|||:||||||||||
Zfish   391 KRLDLAGPLLAFLFRGMFKNLLKEIRIYAQKFIDRGKDFNLELAIKTRIISDGLKYSLATGNWGD 455

  Fly   457 QKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMLCPAETPEGAAV 521
            .||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||.||
Zfish   456 VKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAV 520

  Fly   522 GLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMA 586
            ||||||||||||||||||||||||||||||||||||:|:||||||||||||||||||:||||||.
Zfish   521 GLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMN 585

  Fly   587 TLRKLRRQMDIIVSEVSMIRDIRDREIRIYTDAGRICRPLLIVENGSLLLKKTHVEMLKERDYNN 651
            |||||||||||||||||||||||:||||||||||||||||||||...||||:.|::.||||:|||
Zfish   586 TLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKRRHIDQLKEREYNN 650

  Fly   652 YSWQVLVASGVVEYIDTLEEETVMIAMSPYDLKQDKDYAYCTTYTHCEIHPAMILGVCASIIPFP 716
            ||||.|||||||||||||||||||:||:|.|| |:|..|||:|||||||||:|||||||||||||
Zfish   651 YSWQDLVASGVVEYIDTLEEETVMLAMTPDDL-QEKGVAYCSTYTHCEIHPSMILGVCASIIPFP 714

  Fly   717 DHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVTTRSMEYLRFRELPAGINSI 781
            ||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||
Zfish   715 DHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSI 779

  Fly   782 VAILCYTGYNQEDSVILNASAVERGFFRSVFYRSYKDSENKRVGDQEENFEKPHRGTCQGMRNAH 846
            |||..|||||||||||:|.|||:|||||||||||||:.|:|:..||||.||||.|.||||||:|.
Zfish   780 VAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEIFEKPTRETCQGMRHAI 844

  Fly   847 YDKLDDDGIIAPGIRVSGDDVVIGKTITLPENDDELDSNTKRFSKRDASTFLRNSETGIVDQVML 911
            ||||||||:||||:||||:||:||||:|||||||||||..:|::|||.|||||.||||||||||:
Zfish   845 YDKLDDDGLIAPGVRVSGEDVIIGKTVTLPENDDELDSTNRRYTKRDCSTFLRTSETGIVDQVMV 909

  Fly   912 TLNSEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMAFTCEGLAPDIIINPHAIPS 976
            |||.|||||||||||||||||||||||||||||||||||||||||.|||||:.||||||||||||
Zfish   910 TLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIINPHAIPS 974

  Fly   977 RMTIGHLIECLQGKLGSNKGEIGDATPFNDAVNVQKISTFLQEYGYHLRGNEVMYNGHTGRKINA 1041
            |||:||||||||||:.:|||||||||||||||||||:|..|.|||||||||||:|||.||||:.:
Zfish   975 RMTVGHLIECLQGKVSANKGEIGDATPFNDAVNVQKVSNLLSEYGYHLRGNEVLYNGFTGRKLTS 1039

  Fly  1042 QVFLGPTYYQRLKHMVDDKIHSRARGPVQILVRQPMEGRARDGGLRFGEMERDCQISHGAAQFLR 1106
            |:|:|||||||||||||||||||||||||||.|||||||:||||||||||||||||:|||||||:
Zfish  1040 QIFVGPTYYQRLKHMVDDKIHSRARGPVQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLK 1104

  Fly  1107 ERLFEVSDPYRVHICNFCGLIAIANLRNNTFECKGCKNKTQISQVRLPYAAKLLFQELMSMNIAP 1171
            |||||.||||:||:||.|||:||||.|.:|:||:||:||||||.||:|||.||||||||||:|||
Zfish  1105 ERLFEASDPYQVHVCNLCGLMAIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAP 1169

  Fly  1172 RLMVT 1176
            |:|.:
Zfish  1170 RMMTS 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpII140	NP_001287323.1	PRK08565	28..1176	CDD:236291	994/1147 (87%)
polr2b	NP_001019632.2	PRK08565	27..1172	CDD:236291	993/1145 (87%)
		RNA_pol_B_RPB2	39..1172	CDD:238353	983/1133 (87%)
		RNA_pol_Rpb2_4	567..629	CDD:282431	58/61 (95%)
		RNA_pol_Rpb2_5	653..700	CDD:282432	38/47 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580579
Domainoid	1	1.000	716	1.000	Domainoid score	I109
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H722
Inparanoid	1	1.050	2059	1.000	Inparanoid score	I44
OMA	1	1.010	-	-		QHG62192
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	1	1.000	-	-		oto41250
orthoMCL	1	0.900	-	-		OOG6_100190
Panther	1	1.100	-	-	LDO	PTHR20856
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X610
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.910