Protein Alignment twf and TWF2

DIOPT Version :9

• Sequence 1: NP_650338.1
• Gene: twf / 41719
• FlyBaseID: FBgn0038206
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_009215.1
• Gene: TWF2 / 11344
• HGNCID: 9621
• Length: 349
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 171/345 - (49%)
• Similarity: 235/345 - (68%)
• Gaps: 2/345 - (0%)

  Fly     1 MSHQTGIRANEQLAKVFGKAKNGKFRVIKVSIENEQLSCGATAETKKDWERDYDKLIGPLLEKDV 65
            |:|||||.|.|:|.:.|.||:.|..|:|||.||:|||..||:.|....|::|||:.:.|||:...
Human     1 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQQ 65

  Fly    66 PCYILYRLDAKIPLGYSWLLISWTPDTASIRQKMVYASTKATLKTEFGSAYITEELHATTLDECT 130
            |||:|||||::...|:.||.::|:||.:.:|.||:||:|:||:|.|||..:|.:||..|..|:.:
Human    66 PCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDLS 130

  Fly   131 LEGYRRHKQDFAAPAPLTSREEELKELRKTEVHTEINTNTRHQTLGGINCPLSEATVAAVQDLVR 195
            ..||::|....||||||||.|.||:::|..||.|||:..::||||.|:..||......|:|.|.:
Human   131 FAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQ 195

  Fly   196 GKHDYLQFRIDLEEEQIHVSRAAKVELADLPKQVPEDHARYHLFLFRHTHEGDYFESYVFVYSMP 260
            ...:|:|.::|||.|.|.:......::|.||.:||.|.||||.||::||||||..||.||:||||
Human   196 KMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFLYKHTHEGDPLESVVFIYSMP 260

  Fly   261 GYSCSVRERMMYSSCKAPFLDELAA-LGVEVVKKLEIDSGSELTEAFLQDELHPKKILHRPAFAK 324
            ||.||::|||:|||||:..||.:.. ..:|:.||:||..|:|||..||.||:|||:...:.||||
Human   261 GYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDGAELTAEFLYDEVHPKQHAFKQAFAK 325

  Fly   325 PKGP-PNRGAKRLTRPTAED 343
            |||| ..||.|||.|...|:
Human   326 PKGPGGKRGHKRLIRGPGEN 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twf	NP_650338.1	ADF_Twf-N_like	4..142	CDD:200441	64/137 (47%)
		ADF_Twf-C_like	176..310	CDD:200440	64/134 (48%)
TWF2	NP_009215.1	ADF_Twf-N_like	4..142	CDD:200441	64/137 (47%)
		ADF_Twf-C_like	176..311	CDD:200440	64/134 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..349		15/24 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159562
Domainoid	1	1.000	136	1.000	Domainoid score	I4931
eggNOG	1	0.900	-	-		E1_KOG1747
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2144
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54608
OrthoDB	1	1.010	-	-		D1578109at2759
OrthoFinder	1	1.000	-	-		FOG0001842
OrthoInspector	1	1.000	-	-		otm42265
orthoMCL	1	0.900	-	-		OOG6_102985
Panther	1	1.100	-	-	LDO	PTHR13759
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1569
SonicParanoid	1	1.000	-	-		X134
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800