DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Abi and ABIL1

DIOPT Version :9

Sequence 1:	NP_001247091.1	Gene:	Abi / 41718	FlyBaseID:	FBgn0020510	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001118534.1	Gene:	ABIL1 / 819230	AraportID:	AT2G46225	Length:	329	Species:	Arabidopsis thaliana

Alignment Length:	360	Identity:	73/360 - (20%)
Similarity:	131/360 - (36%)	Gaps:	87/360 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQI 77
            :||::...........|.|::....|...|||||.:|..::.|:..|:..|:||.::|.:....:
plant    15 LDEVSMERNKSFVKALQELKNLRPQLYSAADYCEKSYLHSEQKQMVLDNLKDYTVKALVNAVDHL 79

  Fly    78 NTLAYSYMQLLELQAQQLGEMESQMNHIAQ---TVHIHKEKVARREIGVLTANKVSSRQFKIVAP 139
            .|:|.....|.:.|...:..||.:.:.::|   |...:.:|...|:           :|...|.|
plant    80 GTVASKLTDLFDHQNSDISTMEMRASCVSQQLLTCRTYIDKEGLRQ-----------QQLLAVIP 133

  Fly   140 INPEKPI--KYVRKPIDYSMLDEIGHGINSAQHSQVRQKH-----RGSSHGSVQSLLPPSVGPPP 197
            ::.:..|  ..|.|.:.:|.|          :.:..||.|     |....|::.|.|...|
plant   134 LHHKHYILPNSVNKRVHFSPL----------RRTDTRQNHYQAISRLQPSGAMSSSLSLLV---- 184

  Fly   198 TTKPPTPPQMSRAGNTGT-LGKSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGHPKRMS 261
                         .||.: :..|:||  .||.:..:           .|:..:.::.:|...: |
plant   185 -------------NNTSSQISNSLSN--MLGLTHLD-----------APASKSLSWHLGSETK-S 222

  Fly   262 TASSTMTTTTTGGGAAGNERAAGYSALPMPPSQQIATHVNLPSAGMMQSLPPPPPTTYDDRSSMP 326
            |...|.|...:...:....:.:|...| :...:.||.  ..|.||...|..|...|.:.|..
plant   223 TLKGTSTVAPSSKDSKAFSKTSGVFHL-LGDDENIAN--KKPLAGSQVSGVPAASTAHKDLE--- 281

  Fly   327 PAPPSPLTVSQHEMTEQSHIGMHTLGRNINRNPNR 361
                .|..::.|              |:::.||.|
plant   282 ----VPKLLTAH--------------RSLDNNPRR 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abi	NP_001247091.1	Abi_HHR	105..168	CDD:400255	12/67 (18%)
Abi	NP_001247091.1	SH3_Abi	423..474	CDD:212760
ABIL1	NP_001118534.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2546
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10460
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000