Protein Alignment Abi and ABI3

DIOPT Version :9

• Sequence 1: NP_001247091.1
• Gene: Abi / 41718
• FlyBaseID: FBgn0020510
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_005257486.1
• Gene: ABI3 / 51225
• HGNCID: 29859
• Length: 373
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 165/479 - (34%)
• Similarity: 225/479 - (46%)
• Gaps: 124/479 - (25%)

  Fly    13 MDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQI 77
            |.||..|...|||.||::||.:::.|.||||||||.|.:|.:|:.|||.|..:|||:|||||||:
Human     1 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQV 65

  Fly    78 NTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVL-TANKVSSRQFKIVAPIN 141
            ..||...:::|:||...|.::|::::.:.|.|::|.|||||||||.| |..::...| |::||.|
Human    66 GNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQ-KVIAPEN 129

  Fly   142 PEKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSLLPPSVGPPPTTKPPTPPQ 206
            ......|.|:|:::..||:|||||..
Human   130 LPPLTPYCRRPLNFGCLDDIGHGIKD--------------------------------------- 155

  Fly   207 MSRAGNTGTLGKSVSNTGTLGKSSREYRTPP----VVNPPQVPSH-YAPNYPIGHPKRMSTASST 266
                     |...:|.||||.:.|.:....|    :..||::|.. :.|..|.|   |:|.|||.
Human   156 ---------LSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDG---RLSAASSA 208

  Fly   267 MTTTTTGG--GAAGNERAAGYSALPMPPSQQIATHVNLPSAGMMQSLPPPPPTTYDDRSSMPP-- 327
            .:..:.|.  |..|.....|.:|.|.||         |||     ||.||||....:....||
Human   209 FSLASAGSAEGVGGAPTPKGQAAPPAPP---------LPS-----SLDPPPPPAAVEVFQRPPTL 259

  Fly   328 ---APPSPLTVSQHEMTEQSHIGMHTLGRNINRNPNRNHFSLNFARPGSQSPPLP---PPPPPED 386
               :||.|.                              |.|   .|..:..|||   |||||.|
Human   260 EELSPPPPA------------------------------FLL---FPQDEELPLPLDLPPPPPLD 291

  Fly   387 EHQDFGRPRTSTGPQLAPIVPEDQNLPGWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKK 451
             ..:.|.|....|     ..|::   |.|||.:::||||.:|.|.:.||:||||.|.:|:.|.::
Human   292 -GDELGLPPPPPG-----FGPDE---PSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRR 347

  Fly   452 NDDGWWEGVMDGVTGLFPGNYVEP 475
            ..|||.|||....||.||||||||
Human   348 YSDGWCEGVSSEGTGFFPGNYVEP 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abi	NP_001247091.1	Abi_HHR	105..168	CDD:400255	29/63 (46%)
		SH3_Abi	423..474	CDD:212760	27/50 (54%)
ABI3	XP_005257486.1	Abi_HHR	93..164	CDD:285106	31/119 (26%)
		SH3_Abi	319..370	CDD:212760	27/50 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2546
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1478981at2759
OrthoFinder	1	1.000	-	-		FOG0001315
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10460
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850