DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Abi and abi1

DIOPT Version :9

Sequence 1:	NP_001247091.1	Gene:	Abi / 41718	FlyBaseID:	FBgn0020510	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	XP_012820001.1	Gene:	abi1 / 493216	XenbaseID:	XB-GENE-942152	Length:	502	Species:	Xenopus tropicalis

Alignment Length:	542	Identity:	216/542 - (39%)
Similarity:	285/542 - (52%)	Gaps:	127/542 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQI 77
            |.||..|:..|||.|:::|.:|:.||.|||||||..|.:|.:|:.|||.||.|||||||||||||
Frog     1 MAELQMLLEEEIPAGKKALIESFHNLTRVADYCESNYIQAPDKRKALEETKAYTTQSLASVAYQI 65

  Fly    78 NTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINP 142
            |.||.:.:|||::||.||..|||.:|||:|||.||||||||||||:||.||.::|..||:||.|.
Frog    66 NALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTARSHKIIAPANM 130

  Fly   143 EKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSLLPPSVGPPPTTKPPTPPQM 207
            |:|::|:||||||::||::|||:     ..::.||.|:......:|...:   |||.|||:||..
Frog   131 ERPVRYIRKPIDYTVLDDVGHGV-----KWLKAKHGGNQAARTGTLTRTN---PPTQKPPSPPMP 187

  Fly   208 SRAGNTGTLGKSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGHPKRMS-------TASS 265
            .|              ||||::: .|:|...|.||.||:.|..:     |.|:.       |||.
Frog   188 GR--------------GTLGRNT-PYKTLEPVKPPTVPNDYMTS-----PARLGSQHSPGRTASL 232

  Fly   266 TMTTTTTGG--GAAGNERAAGYSALPMP-----PSQQIATHVNLPSAGM-MQSLPPPPPTTYDDR 322
            .....|..|  |.:|:...:|.|::.:|     ||.        |:.|. :...|||||
Frog   233 NQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSP--------PTIGQGISGGPPPPP------ 283

  Fly   323 SSMPPAPPSPLT----------------VSQHEMTEQS----------HIGMHTLGR-NINRNPN 360
            :..||.||.|..                :|:|..|..|          .:.....|: ::|..|.
Frog   284 APPPPPPPPPAVGTGSAPGSQFGSMTRQISRHNSTTSSASSGGYRRTPSVTSQFSGQPHVNGGPL 348

  Fly   361 RNHFSLNFARPGSQSP----------------------PLPPPPPPEDEHQDFGRPRTSTGPQLA 403
            .:..|::.|.|....|                      |.||||||.||     .|.....|...
Frog   349 YSQNSISIASPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDE-----IPMFDDSPPPP 408

  Fly   404 PIVPED----------------QNLPGWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKN 452
            |..|.|                ...|.|.||:::|||||||||..||:|||||.|.:::||:|||
Frog   409 PPPPVDYEEEEAAVVQYNDPYADGDPIWAPKSYLEKVVAIYDYSKDKEDELSFMEGAIIYVIKKN 473

  Fly   453 DDGWWEGVMDGVTGLFPGNYVE 474
            ||||:|||.:||||||||||||
Frog   474 DDGWYEGVSNGVTGLFPGNYVE 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abi	NP_001247091.1	Abi_HHR	105..168	CDD:400255	40/62 (65%)
Abi	NP_001247091.1	SH3_Abi	423..474	CDD:212760	38/50 (76%)
abi1	XP_012820001.1	Abi_HHR	93..169	CDD:369536	43/80 (54%)
abi1	XP_012820001.1	SH3	444..502	CDD:388381	40/52 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5886
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2350
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1478981at2759
OrthoFinder	1	1.000	-	-		FOG0001315
OrthoInspector	1	1.000	-	-		otm48211
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5876
SonicParanoid	1	1.000	-	-		X1741
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090