DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kif19A and AT5G02370

DIOPT Version :9

Sequence 1:	NP_996208.1	Gene:	Kif19A / 41717	FlyBaseID:	FBgn0038205	Length:	750	Species:	Drosophila melanogaster
Sequence 2:	NP_195857.3	Gene:	AT5G02370 / 831740	AraportID:	AT5G02370	Length:	564	Species:	Arabidopsis thaliana

Alignment Length:	586	Identity:	156/586 - (26%)
Similarity:	233/586 - (39%)	Gaps:	160/586 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 VAVRVRP------SMEATE--RCIEVISGGSLLYDDGGKS-------------RPRQYSYDHVF- 80
            |.:||||      |.|:.:  .|:.||.|      |||.:             |...|..|..:
plant    23 VVLRVRPFLPREISDESCDGRSCVSVIGG------DGGDTSEVAVYLKDPDSCRNESYQLDAFYG 81

  Fly    81 RENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTASCD 145
            ||:|:.:.::....:||:..:.:|.||.|.||||||||||.||.|         .|..|
plant    82 REDDNVKHIFDREVSPLIPGIFHGFNATVLAYGATGSGKTFTMQG---------IDELP------ 131

  Fly   146 STDVSSQDIGLMVRAIEDIFSHIESAEAYSCRVSISYLEIYNELIRDLLN-PGGPLELREDHRGQ 209
                     |||...:..|.|..|...:   |..|||.|:|.:...|||. ....:.:.:|..||
plant   132 ---------GLMPLTMSTILSMCEKTRS---RAEISYYEVYMDRCWDLLEVKDNEIAVWDDKDGQ 184

  Fly   210 RITVAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPLGTKQGRLF 274
             :.:.|||.:...|..|.....|.|.:.|.:..|..|..|||||.:|.|.|   |..|...|::.
plant   185 -VHLKGLSSVPVKSMSEFQEAYLCGVQRRKVAHTGLNDVSSRSHGVLVISV---TSQGLVTGKIN 245

  Fly   275 LTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLSGGARYVNYRDSKLTRLLKEALSGR 339
            |.||||:|..::|.|.|.||||.|.||:||.||.||:..|:.....|.||::||||:|:::|.|.
plant   246 LIDLAGNEDNRRTGNEGIRLQESAKINQSLFALSNVVYALNNNLPRVPYRETKLTRILQDSLGGT 310

  Fly   340 CKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFK---DFPTKHYQSLVSELRD 401
            .:.:|:|.:.|  ....|:..|:..|.|:..|:..:..:..::..|   |...|....|  |.:.
plant   311 SRALMVACLNP--GEYQESLRTVSLAARSRHISNNVSLNPKVETPKVKIDMEAKLQAWL--ESKG 371

  Fly   402 EVSRLRTKMLTERPRSGAAAAAAA-----------AAASGSAGTAGSG----------------- 438
            ::......|....|..|....:.:           :|.:.||..||:|
plant   372 KMKSAHRMMAIRSPLMGTNQTSISQSSVKKLLCHRSAIAESAKLAGTGQRDAFVTARNLFGVETL 436

  Fly   439 AGSE----------AVQEQDEQRKTELRYLREQIVLTFKQQMKLRRKLLEAESHLLGLELDAERQ 493
            |.|.          |...::::|.|                 .....||.:|:.|....||.|::
plant   437 AASHLWEPIRNLQLASPTKEDERDT-----------------SGEENLLVSEASLRDNTLDVEKK 484

  Fly   494 HMIISHWQGRIGKLYDAMGDDD-------------------------------IESEGSVALKNA 527
            :..:|       .|.:|:...|                               ::.||:....||
plant   485 YTELS-------PLREALSPIDSNAKPNSAHGSSPFLKPMTPKTPFLSTNPEIMQMEGTCQKFNA 542

  Fly   528 W 528
            |
plant   543 W 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	120/355 (34%)
Kif19A	NP_996208.1	Kinesin	41..371	CDD:278646	119/352 (34%)
AT5G02370	NP_195857.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000448
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810