Protein Alignment Kif19A and POK2

DIOPT Version :10

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_188535.4
• Gene: POK2 / 821439
• AraportID: AT3G19050
• Length: 2771
• Species: Arabidopsis thaliana
• Alignment Length: 834
• Identity: 218/834 - (26%)
• Similarity: 359/834 - (43%)
• Gaps: 230/834 - (27%)

  Fly     7 ASSWSG--SSGGSNSSQGRSIATAQPAQEE--------RLVVAVRVRP--SMEAT----ERCIEV 55
            ||.:.|  ||.|..|:...|:.....:.:|        .:.:.:||||  |||.:    .||::.
plant   155 ASLYKGLSSSSGQVSTVVNSVEVPHFSLKEDPSFWMDHNVQILIRVRPLNSMERSINGYNRCLKQ 219

  Fly    56 ISGGSLLYDDGGKSRPRQYSYDHVFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKT 120
            .|...:.:....::|   :.:|||..|...||.:::....|:|.:.|:|.|:.:||||.||||||
plant   220 ESSQCVAWIGPPETR---FQFDHVACETIDQETLFRVAGLPMVENCLSGYNSCIFAYGQTGSGKT 281

  Fly   121 HTMLGPVP--RKKPQTSDRAPPTASCDSTDVSSQDIGLMVRAIEDIFSHIESAE--------AYS 175
            :||||.|.  ..||                  |.:.|:|.|..|.:|:.|::.|        .|:
plant   282 YTMLGEVGDLEFKP------------------SPNRGMMPRIFEFLFARIQAEEESRRDERLKYN 328

  Fly   176 CRVSISYLEIYNELIRDLLNPGGP-LELREDHRGQRITVAGLSEITTSSRKEVVSLLLKGNKART 239
            |:  .|:||||||.|.|||.|... |:||||.: ..:.|..|:|....|.::::.|:.:|:..|.
plant   329 CK--CSFLEIYNEQITDLLEPSSTNLQLREDIK-SGVYVENLTECEVQSVQDILGLITQGSLNRR 390

  Fly   240 MEPTAANQTSSRSHALLSIMVQAR----TPLGTKQGRLFLTDLAGSERAKKTKNRGKRLQEGAHI 300
            :..|..|:.|||||::.:.::::|    :....:..||.|.|||||||.|.:...|.||:|.|.|
plant   391 VGATNMNRESSRSHSVFTCVIESRWEKDSTANMRFARLNLVDLAGSERQKTSGAEGDRLKEAASI 455

  Fly   301 NRSLLALGNVINGL----SGGARYVNYRDSKLTRLLKEALSGRCKTVMIAHVAPESKHRDETKNT 361
            |:||..||:||..|    :|..|::.||||:||.||:::|.|..||::||:.:|......||.||
plant   456 NKSLSTLGHVIMVLVDVANGKPRHIPYRDSRLTFLLQDSLGGNSKTMIIANASPSVSCAAETLNT 520

  Fly   362 LVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVSELRDEVSRLRTKMLTERPRSGAAAAAAAA 426
            |.:|.||..|    ||:..::|..:......:..:..|::|:|.|:.:.::.....|:|.|..|.
plant   521 LKFAQRAKLI----QNNAVVNEDSNEDVLELRRQIRLLKEELSLLKRQNISRALSFGSATANFAE 581

  Fly   427 AASGSAG-----TAGSGAGSEAVQEQD-------------------------------EQRKTEL 455
            :...|..     |....||:..|.|..                               ::.:.|:
plant   582 SQVDSPSSVMHETGQQQAGNLLVYESGGCVRMSRKQLKSLEITLAGSLRREHVADASIKKLEAEI 646

  Fly   456 RYL------REQIVLTFKQQMKLRRKLLEAESHLLGLELDAE----RQHMIISH----WQGRIGK 506
            .:|      ||:...:.|..::.|...::....|||..:.|:    .::.::|.    .|.:|.|
plant   647 EHLNRLVRQREEDTRSTKMMLRFREDKIQRLESLLGNHISADSFLLEENNVLSEEIQLLQAKIDK 711

  Fly   507 -------------LYDAMG---------------------------------------DDDIESE 519
                         |.|.:.                                       ||.||.:
plant   712 NPELTRFALENIRLLDQLRRFQEFYEEGEREILLGEVSNLRNQLFQFLDENSDWQKHVDDGIEPQ 776

  Fly   520 GSVALKNAWGELAAIEKETRRYKEIRERTEHELEQCR-------QKGVKLEDEL----------- 566
            |:          :.:.||....:|..::|.:|||:||       ::..||..|:
plant   777 GA----------SRMSKENCSLQEELKKTCYELEKCRSNLGSCLEENAKLSREINDLQAMVSDIR 831

  Fly   567 ---PERISS-DEERELL---------ALLCR----VHE-------LEADKVSLQAERLAR----- 602
               |:..|| ::::.||         .|.|.    |.|       |:..|:.|..||..|
plant   832 ACTPDEHSSVNKQKALLGTQNFEPHETLACEQANYVEEIIKLQLDLDVQKIILDEERTLRGDTEA 896

  Fly   603 QAELRRRDLQLLR------AERQRRLCEDI--ISSQRRLIEEGNVDLPDELREL 648
            ||...:.|:::|:      :::|:.:..::  ..|....:|..|:.|..|..||
plant   897 QAVRLKFDIEVLKDQLLLISKQQKNVYSELGETKSAVAALESQNIILIQEAVEL 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:473979	131/360 (36%)
		SMC_prok_B	<393..672	CDD:274008	74/413 (18%)
POK2	NP_188535.4	Motor_domain	192..540	CDD:473979	135/375 (36%)
		PLN03188	<614..>763	CDD:215621	16/148 (11%)
		SMC_prok_B	615..>1344	CDD:274008	60/346 (17%)
		SMC_N	<1262..1598	CDD:481474
		SMC_prok_B	<1674..2384	CDD:274008
		Smc	<2131..>2674	CDD:440809