Protein Alignment Kif19A and Klp54D

DIOPT Version :10

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Alignment Length: 797
• Identity: 191/797 - (23%)
• Similarity: 309/797 - (38%)
• Gaps: 248/797 - (31%)

  Fly     6 GASSWSGSSGGSN-------SSQGRSIATAQPAQ---------------EERLVVAVRVRPSMEA 48
            |:|..:|..|||:       .|:...|.:|...:               |:.:.|.|||||..:.
  Fly   115 GSSGGTGGGGGSSRNTPYFLRSRENEIGSADTLEIVASKSTGSEECSTPEDNINVVVRVRPLNDK 179

  Fly    49 TER-----CIEVISGGSLLYD--DGGKSRP------RQYSYDHVFRENDSQEQVYKTTTAPLVRD 100
            .:|     .::....|.::.:  |.|:.|.      |.::|:.||....:||.:...:....:.:
  Fly   180 EKRDRHGSTLQFPGNGQVILEGNDVGQKRSHNRDSVRVFTYNVVFEPGATQEDILDYSGIKRIIE 244

  Fly   101 V-LNGLNAAVFAYGATGSGKTHTMLGPVPR--KKPQTSDRAPPTASCDSTDVSSQDIGLMVRAIE 162
            : :.|.:...|.||.||||||||:.||...  .||...|...               ||:.|:..
  Fly   245 MGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRH---------------GLIFRSFL 294

  Fly   163 DIFSHIESAEAYSCRVSISYLEIYNELIRDLLNPGG---PLELREDHRGQRITVAGLSEITTSSR 224
            .:|..|::.:..:..:..|::|||||.:.||||||.   ||.:|...:.....|..|..:.....
  Fly   295 YLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSKKSGGFFVENLFTVDCEEL 359

  Fly   225 KEVVSLLLKGNKARTMEPTAANQTSSRSHALLS--IMVQARTPLG---TKQGRLFLTDLAGSERA 284
            .:::::|.:|.:.|.:...|.|..|||||.:|:  |:...:|..|   :|.|::...||||||..
  Fly   360 DDLLAVLEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGGVFLSKHGKINFVDLAGSELT 424

  Fly   285 KKTKNRGKRLQEGAHINRSLLALGNVINGLSGGAR---YVNYRDSKLTRLLKEALSGRCKTVMIA 346
            |||.:.||.|:|..:||:||:.||..|:.||...:   ::.||||:||:||.::|:|...|:|||
  Fly   425 KKTMSEGKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPYRDSQLTKLLADSLAGNGVTLMIA 489

  Fly   347 HVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVSELRDEVSRLRTKML 411
            .|:|...:..||.|||.||.||                                   .|:|||
  Fly   490 CVSPAHYNHAETLNTLRYASRA-----------------------------------KRIRTK-- 517

  Fly   412 TERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLREQIVLTFKQQMKLRRKL 476
                                           .|.:.|.         ||.::|:.|:.:
  Fly   518 -------------------------------PVIKMDP---------REALILSLKRDI------ 536

  Fly   477 LEAESHLLGLELDAERQHMIISHWQ----GRIGKLYDAMGDDDIESEGSVALKNAWGELAAIEKE 537
                 |.|.:|.|..:..:.:.|..    |.:..|.: :..|.:.|.|.|.:..
  Fly   537 -----HALQMENDHLKAALNLHHQAAPNGGPVENLLE-LQLDRVSSGGGVPVPK----------- 584

  Fly   538 TRRYKEIRERTEHELEQCRQKGVKLEDELPERISSDEERELLALLCRVHELEADKVSLQAERLAR 602
                                  |.|: .|||...|:     ||.|.:::.:|.:.:..:...|..
  Fly   585 ----------------------VDLQ-RLPELDGSE-----LAELVKLYMVENESLRQENNHLFT 621

  Fly   603 QAELRRRDLQLLRAERQRRLCEDIISSQRRLIEEGNVDLPDELRELYGLYQQEIHA-GVVTPSTS 666
            ..|...||.:::..|.:|.|        ::|.:...|.:...|          |.| ..::|:|
  Fly   622 VRETILRDQEIVCRENERLL--------KKLEDVNKVCVRSPL----------IPARPAISPTT- 667

  Fly   667 NYERKLPPIYTAGSDSPGSSSSSEWSPASPLPQIDNQMDPVDRVMGPPVNPRLP---RLSAATSA 728
                        |.::||:..   |:...||             ..|| .|.||   |:|...:.
  Fly   668 ------------GKETPGTEI---WTNPEPL-------------QSPP-GPDLPIEQRMSENANR 703

  Fly   729 NVPAGGSRRPSLRVARN 745
            .......|....|:|:|
  Fly   704 RTDTAQKRIDQKRIAKN 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:473979	119/362 (33%)
		SMC_prok_B	<393..672	CDD:274008	45/283 (16%)
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	123/436 (28%)