Protein Alignment Kif19A and sub

DIOPT Version :9

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 760
• Identity: 168/760 - (22%)
• Similarity: 270/760 - (35%)
• Gaps: 272/760 - (35%)

  Fly    17 SNSSQGRSIATAQPAQEERLV-----VAVRVRPSMEATERCIEVISGGSLL-------YDDGGKS 69
            |.:::|.|.||:  |.:...|     |.:|:||..:|::..|.......|:       ..:....
  Fly    66 SEATEGASCATS--AADSSNVETGPQVFLRLRPVKDASKAYIVSEEANVLITSCKVDSTSNNVNR 128

  Fly    70 RPRQYSYDHVFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGP------VP 128
            ..:.:.:..:|.....|..:|.|...|   .::......:..||.:|||||:|:||.      :|
  Fly   129 MEKHFGFTSIFDSTVGQRDIYDTCVGP---KIMEEECVTIMTYGTSGSGKTYTLLGDDVRAGIIP 190

  Fly   129 RK-------KPQTSDRAPPTASCDST------DVSSQDIGLMVRAIE---DIFSH-------IES 170
            |.       ...|..|:|.....:.:      |.|.:::.:..:.::   ||.:|       |:.
  Fly   191 RALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDG 255

  Fly   171 AEAYSCRVS--------ISYLEIYNELIRDLLNPGGPLELREDHRGQ-------------RITVA 214
            ...:..:.|        :|::||||||:.|||    .:..::|..|:             .:.:.
  Fly   256 DHMFETKASTDVSVLVWVSFVEIYNELVYDLL----AIPPKQDKLGEVPRKNLKIVGNKGHVFIK 316

  Fly   215 GLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPLG-TKQGRLFLTDL 278
            ||:.:..:|.:|.:.||..|.:..|...|:.|..|||||.:.::.:......| |.|......||
  Fly   317 GLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKFCDL 381

  Fly   279 AGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLS-----GGARYVNYRDSKLTRLLKEALSG 338
            |||||...|...|.||:|..:||.||:.||..::..|     ..|..:.|||||||.||:.||.|
  Fly   382 AGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLG 446

  Fly   339 RCKTVMIAHVAPESKHRDETKNTLVYADRANSITTK----LQNSVYIDEFKDFPTKHYQSLVSEL 399
            :.|..||..|.|..|:.:|..|.|.:|..|.:|..|    .|:.|....|.:|
  Fly   447 KEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYCGFMEF------------ 499

  Fly   400 RDEVSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLREQIVL 464
                    :||                      .|...|..::.:::::.:.:.|:..|:...||
  Fly   500 --------SKM----------------------STCEGGDYTKELEDENVRLQLEIEQLKYDHVL 534

  Fly   465 TFK-QQMKLRRKLLEAESHLLGLELDAERQHMIISHWQGRIGKLYDAMGDDDIESEGSVALKNAW 528
            ..: .:.||||:|
  Fly   535 QMQLLEEKLRREL---------------------------------------------------- 547

  Fly   529 GELAAIEKETRRYKEIRERTEHELE-QCRQKGVKLEDELPERISSDEERELLALLCRVHELEADK 592
                     |..|:||.:..:.:.| :|.:|
  Fly   548 ---------TATYQEIIQNNKKQYEDECEKK---------------------------------- 569

  Fly   593 VSLQAERLARQAELRRRDLQLLRAERQRRLCEDIISSQRRLIEEGNVDLPDELRELYGLYQQEIH 657
                                ||.|:|:   .|.::|||||..||...||.||:.||
  Fly   570 --------------------LLIAQRE---SEFMLSSQRRRYEEQIEDLKDEIEEL--------- 602

  Fly   658 AGVVTPSTSNYERKLPPIYTAGSDSPGSSSSSEWSPASPLPQIDN 702
                         |.|...|..||.|..|.       ||:..:|:
  Fly   603 -------------KNPASDTDISDDPNESK-------SPIEILDD 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	108/403 (27%)
		Kinesin	41..371	CDD:278646	106/392 (27%)
sub	NP_001286548.1	KISc	89..477	CDD:276812	106/394 (27%)
		Kinesin	93..479	CDD:278646	106/392 (27%)
		GBP_C	<512..603	CDD:303769	34/230 (15%)
		coiled coil	576..586	CDD:293879	4/12 (33%)
		coiled coil	592..603	CDD:293879	6/32 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437856
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940