Protein Alignment Kif19A and Klp68D

DIOPT Version :9

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_001261726.1
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 822
• Identity: 236/822 - (28%)
• Similarity: 355/822 - (43%)
• Gaps: 186/822 - (22%)

  Fly    16 GSNSSQGRSIATAQPAQEERLVVAVRVRP--SMEATERCIEVISGGSLLYD-----------DGG 67
            |:.|||         ...|.:.|.||.||  :.|.:||..||::    :|.           ||.
  Fly     9 GTGSSQ---------TPNECVQVVVRCRPMSNRERSERSPEVVN----VYPNRGVVELQNVVDGN 60

  Fly    68 KSRPRQYSYDHVFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKP 132
            |.:.:.::||..:..:.:|..:|.....|||..||.|.|..:||||.||:|||.||.|
  Fly    61 KEQRKVFTYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEG------- 118

  Fly   133 QTSDRAPPTASCDSTDVSSQD--IGLMVRAIEDIFSHIESAEAYSCRVSISYLEIYNELIRDLLN 195
                            |...|  :|::.|..|.|:.||...|.:...|.:||||||.|.:||||.
  Fly   119 ----------------VRGNDELMGIIPRTFEQIWLHINRTENFQFLVDVSYLEIYMEELRDLLK 167

  Fly   196 PGGP-LELREDHRGQRITVAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIM 259
            |... ||:||  ||..:.|..|..|...|.::::.::..|||.||:..|..|:.||||||:..|.
  Fly   168 PNSKHLEVRE--RGSGVYVPNLHAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIK 230

  Fly   260 VQ-ARTPLGT-KQGRLFLTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLSGGARYVN 322
            :: ..|...| |.|:|.|.|||||||..||....:||:|.:.||.:|.:|||||:.|:..:.:|.
  Fly   231 IEMCDTETNTIKVGKLNLIDLAGSERQSKTGASAERLKEASKINLALSSLGNVISALAESSPHVP 295

  Fly   323 YRDSKLTRLLKEALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNS-VYIDEFKD 386
            ||||||||||:::|.|..||:|||::.|.:.:.:||..||.||.||.||    ||. :..::.:|
  Fly   296 YRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSI----QNQPIKNEDPQD 356

  Fly   387 FPTKHYQSLVSEL----------RDEVSRLRTKMLTERPRSGAAAAAAAAAASGSA-------GT 434
            ...|.||..:..|          |.|......|...::|:........:.:...|.       .:
  Fly   357 AKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKKQRVKKPKKETVTKEMSDSLQVSTIEQPVEDDS 421

  Fly   435 AGSGAGSEAVQEQDEQRKTELRYLREQIVLTFKQQMKLRRKLLEAESHLLGLELDAERQHMIISH 499
            ...||.||:    |::.:.|:....|::.....:..||..||.|.|..|:
  Fly   422 DPEGAESES----DKENEAEVAKSNEELERERVENSKLAAKLAELEGQLV--------------- 467

  Fly   500 WQGRIGK-LYDAMGDDDIESEGSVALKNAWGELAAIEK---ETRRYKEIRERTEHELEQCRQKGV 560
               |.|| |.|...:..||.|..:.      |:|..:|   |.::..|::|.|..|:   |::.|
  Fly   468 ---RGGKNLLDTYSERQIELEKKLV------EIAERKKREIEIQQQLELQEETTLEI---RERNV 520

  Fly   561 KLED--ELPERISSDEERELLALLCRVHELEAD-KVSLQAERLARQAELRRRDLQLL-------- 614
            .||.  ||.:|..|....:.|||...:::.::| ...|:...:|:...::....|||
  Fly   521 SLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNELVKELKRQLLIIDNFVPI 585

  Fly   615 ----RAERQRRLCED--------------------------IISSQRR------LIEEGNVDLPD 643
                |...|.:..|:                          :...|||      .::|...:.|.
  Fly   586 EVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGDGKFSSKRPVSHPQRRRPTSEYALQEAKSNSPS 650

  Fly   644 ELRELYGLYQQEIHAGVVTPSTSNYERKLPPIYTAGSDSPGSSSSSEWSPASPLPQIDNQMDPVD 708
            .||     ::.|        :..|||.::|...|....:|..|:|.:...|..:....:.:|.||
  Fly   651 SLR-----FKSE--------NIVNYELEMPCRTTQEYRTPKVSASLQAVLAQAMQTGGDDIDIVD 702

  Fly   709 RVMGPPVNPRLPRLSAATSANVPAG---------GSRRPSLR 741
                ...|....||....:||...|         ||..|::|
  Fly   703 ----SHTNSLRSRLENIINANANGGAGPGAGVAVGSSIPNVR 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	137/353 (39%)
		Kinesin	41..371	CDD:278646	135/347 (39%)
Klp68D	NP_001261726.1	Motor_domain	18..344	CDD:277568	138/354 (39%)
		KISc	20..351	CDD:214526	141/363 (39%)
		GBP_C	<479..576	CDD:303769	25/105 (24%)
		coiled coil	547..558	CDD:293879	1/10 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438005
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940