Protein Alignment Kif19A and Klp59D

DIOPT Version :9

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Alignment Length: 617
• Identity: 162/617 - (26%)
• Similarity: 254/617 - (41%)
• Gaps: 162/617 - (26%)

  Fly    34 ERLVVAVRVRPSMEATER-----CIEVISGGSLL-------YDDGGKSRPRQYSYDHVFRENDSQ 86
            :::.|.||.||.....|.     .|.|.|..||:       .|........::.:|:.|.|..|.
  Fly   232 QQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVDLTKFLEHHKFRFDYTFDEECSN 296

  Fly    87 EQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTASCDSTDVSS 151
            ..||..|..||:|.:..|.||..||||.|||||||||.|....|                  |..
  Fly   297 ALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGK------------------VQD 343

  Fly   152 QDIGLMVRAIEDIFSHIESAE--AYSCRVSISYLEIYNELIRDLLNPGGP-LELREDHRGQRITV 213
            ...|:...|..|:|..:...|  ....:::.|:.|||...:.|||.|..| |.:.||.| |::.|
  Fly   344 CGTGIYAMAARDVFEEVSRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDAR-QQVVV 407

  Fly   214 AGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPLGTKQGRLFLTDL 278
            .||:|:..:..::|:.|:..|:|.||...|:||..||||||:..|.:......| ..|:....||
  Fly   408 VGLTEMPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWG-PHGKCSFVDL 471

  Fly   279 AGSERAKKTKNRGKRLQ-EGAHINRSLLALGNVINGLSGGARYVNYRDSKLTRLLKEALSG--RC 340
            ||:||...|::..::.: |||.||:|||||...|..||..:.::.:|.||||::|:::..|  :.
  Fly   472 AGNERGADTQSADRQTRIEGAEINKSLLALKECIRALSRQSSHLPFRGSKLTQVLRDSFVGGKKN 536

  Fly   341 KTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVS------EL 399
            ||.|||.::|.....:.|.|||.||||...:..|             ..:|.||:..      :|
  Fly   537 KTCMIAMISPSMSCVENTLNTLRYADRVKELIAK-------------EDEHLQSVEGDGEKSPDL 588

  Fly   400 RDEVSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLREQIVL 464
            .:|   ...:|:.:.                        .|.|..:::|.|.            |
  Fly   589 NEE---SEPEMMADE------------------------EGDEEPEDEDNQH------------L 614

  Fly   465 TFKQQMKLRRKLLEAESHLLGLELDAERQHMIISHWQGRIGKLYDAMGDDDIESEGSVALKNAWG 529
            |...:        ||.|: ..:..|     |..:|....:|...: :...::..:.::.::|
  Fly   615 TISSE--------EASSY-NNMSYD-----MSFNHTLNILGPSRN-VDIQEVAEQHALLVEN--- 661

  Fly   530 ELAAIEKETRRYKEIRERTEHELEQCRQKGVKLEDELPERISSDEERELLALLCRVHELEADKVS 594
                :|.....::::  :|:.|:||..|               :.|..|:.||..|:
  Fly   662 ----LETYAHNFRQL--KTDKEIEQYTQ---------------NSESALMKLLAMVN-------- 697

  Fly   595 LQAERLARQAELRRRDL-------QLLRAERQ 619
                        |.||:       :||:.|.|
  Fly   698 ------------RTRDVTHNYNTQKLLKEENQ 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	123/353 (35%)
		Kinesin	41..371	CDD:278646	121/347 (35%)
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	123/351 (35%)
		Kinesin	239..566	CDD:278646	121/346 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437830
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940