Protein Alignment Kif19A and Khc

DIOPT Version :9

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 720
• Identity: 193/720 - (26%)
• Similarity: 318/720 - (44%)
• Gaps: 190/720 - (26%)

  Fly    30 PAQEERLVVAVRVRPSMEATER----------------CIEVISGGSLLYDDGGKSRPRQYSYDH 78
            || |:.:.|..|.||..::.|:                ||.:          .||    .|.:|.
  Fly     8 PA-EDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISI----------AGK----VYLFDK 57

  Fly    79 VFRENDSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTAS 143
            ||:.|.|||:||......:|.|||.|.|..:||||.|.|||||||.|.:.....|
  Fly    58 VFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQ---------- 112

  Fly   144 CDSTDVSSQDIGLMVRAIEDIFSHIESAEA-YSCRVSISYLEIYNELIRDLLNPGG-PLELREDH 206
                       |::.|.:.|||:||.:.|. ....:.:||.|||.:.|||||:... .|.:.||.
  Fly   113 -----------GIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDK 166

  Fly   207 RGQRIT-VAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPLGTKQ 270
              .|:. |.|.:|...||.::|..::.:|...|.:..|..|:.|||||::..|.|:.......|:
  Fly   167 --NRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKK 229

  Fly   271 --GRLFLTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLSGGAR-YVNYRDSKLTRLL 332
              |:|:|.||||||:..||...|..|.|..:||:||.||||||:.|:.|.: ::.||||||||:|
  Fly   230 LSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRIL 294

  Fly   333 KEALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVS 397
            :|:|.|..:|.::...:|.|.:..|||:||.:..||.::    :|.|.::|  :...:.::....
  Fly   295 QESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTV----KNVVCVNE--ELTAEEWKRRYE 353

  Fly   398 ELRDEVSRLRTK-----MLTERPRSG-------------------------AAAAAAAAAASGSA 432
            :.:::.:||:.|     :...|.|:|                         ||..|||.||..:.
  Fly   354 KEKEKNARLKGKVEKLEIELARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQ 418

  Fly   433 GTA-GSGAGSEAVQEQDEQRKTELRYLREQIVLTFKQQMKLRRKLLEAESHLLGLELDAERQHMI 496
            .|| .:.:.|.||.||                         .|...|.|
  Fly   419 RTALANMSASVAVNEQ-------------------------ARLATECE---------------- 442

  Fly   497 ISHWQGRIGKLYDAMGDDDIESEGSVALKNAWGELAAIEKETRRYKEI--RERTEHELEQCRQKG 559
                     :||..:.|.|.|    :..::.:.|  .::::....:|:  ..|.|:|..|.....
  Fly   443 ---------RLYQQLDDKDEE----INQQSQYAE--QLKEQVMEQEELIANARREYETLQSEMAR 492

  Fly   560 VKLEDELPERISSDEERELLALLCRVHELEADKVSLQAERLARQAELRRRDLQLLRAERQRR--- 621
            ::.|:|    .:.:|.:|:|..|        :::::..::.:::.:.:.:|:..|..|.|::
  Fly   493 IQQENE----SAKEEVKEVLQAL--------EELAVNYDQKSQEIDNKNKDIDALNEELQQKQSV 545

  Fly   622 ---------LCEDIISSQRRLIEEGNVDLPDELRELYGLYQQEIHAGVVTPSTSNYERKLPPIYT 677
                     ..:|:.|.|::.|.|...:|   ||:|..:.|      .:.|..|:.:.|:..:
  Fly   546 FNAASTELQQLKDMSSHQKKRITEMLTNL---LRDLGEVGQ------AIAPGESSIDLKMSAL-- 599

  Fly   678 AGSDS 682
            ||:|:
  Fly   600 AGTDA 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	127/357 (36%)
		Kinesin	41..371	CDD:278646	126/351 (36%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	128/359 (36%)
		KISc	12..340	CDD:214526	129/368 (35%)
		Apolipoprotein	595..744	CDD:279749	4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437990
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940