Protein Alignment Kif19A and neb

DIOPT Version :9

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Alignment Length: 864
• Identity: 224/864 - (25%)
• Similarity: 346/864 - (40%)
• Gaps: 270/864 - (31%)

  Fly    11 SGSSGGSNSSQGRSI--ATAQPAQEERLVVAVRVRP--SMEATE----RCIEVISGGSLLYDDGG 67
            :|.|..|.:.:..|:  :....::|..::|||||||  ::|.|.    ..::|....:.|....|
  Fly    94 TGKSSCSRTKERDSLMESCLSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAG 158

  Fly    68 KSRPRQ------YSYDHVF------RENDS-QEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGK 119
            .|....      :|||.|:      |:|.: |.:|::.|..||:.....|.||.:||||.|||||
  Fly   159 SSADASAGVTHFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGK 223

  Fly   120 THTMLGPVPRKKPQTSDRAPPTASCDSTDVSSQDIGLMVRAIEDIFSHIE---SAEAYSCRVSIS 181
            :::|:| :........|..||          ..:.|::.|...::|..||   |.:.....|.:|
  Fly   224 SYSMMG-IEALDDAALDGGPP----------HDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVS 277

  Fly   182 YLEIYNELIRDLLN-------PGGPLELREDHRGQRIT------------VAGLSEITTSSRKEV 227
            |.|||||.|.|||:       .|....:::..:.||..            |..||..:..|...:
  Fly   278 YFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSAL 342

  Fly   228 VSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQ------------------ARTPLGTKQGRLF 274
            .:.|..||..|....||.|..|||||::.:|::.                  |.:...|::.::.
  Fly   343 RNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKIS 407

  Fly   275 LTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVI-----------NGLSGG---ARYVNYRD 325
            |.|||||||...:.:.|:|::||..||:|||.||.||           ||..|.   :.:|.||:
  Fly   408 LVDLAGSERISVSGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRE 472

  Fly   326 SKLTRLLKEALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTK 390
            |.||.||:|.|.|..||||:|.::|.|.|.|||..||.||.:|.||.    |.|.::|      .
  Fly   473 SVLTWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKARSIV----NRVKVNE------S 527

  Fly   391 HYQSLVSELRDEVSRLRT--------------------------------------KMLTERPRS 417
            .:..::.:||.||.||::                                      :.|.||.|.
  Fly   528 PHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERE 592

  Fly   418 GAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLREQ---IVLTFKQQ---------- 469
            .:.|               ..:..|.::|.::|||:|||.|:.:   :.||.:|:
  Fly   593 LSRA---------------QKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTAD 642

  Fly   470 ---------------MKLRRKLLE--AESHLLGLELD---AERQHMIISHWQGRIGKLYDAMGDD 514
                           :::.|..|.  :.|....:.||   ...||..|.|.:|  ||||...|.:
  Fly   643 PILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERG--GKLYVIPGSE 705

  Fly   515 DIESEGSVALKNAWGELAAIEKETRR-------------------------------------YK 542
            |.|:..:       |||.   |:.|:                                     ::
  Fly   706 DFETYVN-------GELL---KDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQ 760

  Fly   543 EIRERTEHELE-----QCRQKGVKLEDELPERISSDEER------ELLALLCRVHELEADKVSLQ 596
            ||.::.|.:|.     :.|....|:|.|..:.....|||      |.....|....||.::   |
  Fly   761 EILQKQEQQLRSELEAEKRAALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEMLETER---Q 822

  Fly   597 AERLARQAE---LRRRDLQLLRAERQRRLCEDI-----------ISSQRRLIEEG-----NVDLP 642
            |..||:|.|   ||..|.....|::. .:.|||           :...:.:::|.     .:|||
  Fly   823 ALALAQQQEHTPLRHEDAVSTPAQKS-TILEDIQRIMLNPSEESLHKTQLMVKEATQRCRQLDLP 886

  Fly   643 DELREL-----YGLYQQEI 656
            .|.|:.     :||.:..|
  Fly   887 LEFRQTQTPDEFGLLRTVI 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	132/408 (32%)
		Kinesin	41..371	CDD:278646	129/402 (32%)
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	136/420 (32%)
		KISc	120..525	CDD:214526	136/419 (32%)
		Kinesin_assoc	524..657	CDD:292801	24/153 (16%)
		FHA	634..740	CDD:238017	22/117 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437995
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030