Protein Alignment Kif19A and Kif6

DIOPT Version :9

• Sequence 1: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: XP_006244542.1
• Gene: Kif6 / 171291
• RGDID: 621070
• Length: 802
• Species: Rattus norvegicus
• Alignment Length: 717
• Identity: 173/717 - (24%)
• Similarity: 296/717 - (41%)
• Gaps: 158/717 - (22%)

  Fly    33 EERLVVAVRVRPSMEATERCIEVISGGSLLYD-----------DG---GKSRPRQYSYDHVFREN 83
            ::.:.:..||:||:...::.|..|.....|..           ||   .|....::.:..:|.:.
  Rat     3 KQTIQIFARVKPSVRKQQQGIYSIDEDEKLASSLEIVLPRDLADGFVNNKRESYKFKFQRIFDQE 67

  Fly    84 DSQEQVYKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTASCDSTD 148
            ..||.:::....|:....|.|.|..:||||.||||||.|:.|...|    .|||
  Rat    68 AKQEIIFEIIAKPVAESTLAGYNGTIFAYGQTGSGKTFTITGGAER----YSDR----------- 117

  Fly   149 VSSQDIGLMVRAIEDIFSHIESAEAYSCRVSISYLEIYNELIRDLLNPGGPLELRED-------- 205
                  |::.|.:..||..::...:......|||||||||...|||:|.......||
  Rat   118 ------GIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILE 176

  Fly   206 HRGQRITVAGLSEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQARTP--LGT 268
            ...|.|.:..||....::.:|.::||..|:..|.:..|..||.|:|||.:.::.:.::.|  ...
  Rat   177 DPDQNIHLKNLSLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTVHLSSKEPGSATV 241

  Fly   269 KQGRLFLTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLSGGAR-YVNYRDSKLTRLL 332
            :..:|.|.|||||||..||...|..|.|..:||.||..|..||..||...| ::.||:|.:|.:|
  Rat   242 RHAKLHLVDLAGSERVSKTGVGGLLLTEAKYINLSLHYLEQVIIALSEKHRTHIPYRNSMMTSVL 306

  Fly   333 KEALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVS 397
            :::|.|.|.|.|||.::.|.::.||:.:|..:|.|    ...::|...::|..| |    :.::.
  Rat   307 RDSLGGNCMTTMIATLSLEKRNIDESISTCRFAQR----VALIKNEAILNEEID-P----RLMIV 362

  Fly   398 ELRDEVSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLR-EQ 461
            .|:.|::.|:.::               |..:|               ||..:..||...|: |:
  Rat   363 RLQKEIADLKAEL---------------AMVTG---------------EQRTEALTEAELLQLEK 397

  Fly   462 IVLTFKQQMKLRRKLLEAESHL-LGLELDAERQHMIISHWQGRIGKLYDAMGDDDIESEGSVALK 525
            ::.:|.:..       :.||.| :|.:|  .:.|....|::..:.........|..||....|.:
  Rat   398 LIASFVEDQ-------DPESRLEVGADL--RKIHYCFHHFKKLLNDKKTLENTDSSESTTQQACQ 453

  Fly   526 NAWGELAAIEKETRRYKEIRERTEHEL----EQCRQKGVKLEDELPERISSDEERE--------- 577
            .     ...::|..:.:.:.::.::|:    ...:::..|.:|.|  :.||.|:.|
  Rat   454 E-----PVKDEEYTKLRSLLKQRDNEINILVNMLKKEKKKTQDAL--QYSSTEKSEARPPPNSPF 511

  Fly   578 -----------LLALLCRVHELEA---------DKVSLQAE-RLARQA--ELRRRD-LQLLRAER 618
                       ..:.|.:..:|..         .|..::.| .|.||.  |:.:|| ...:..|.
  Rat   512 IAGSPAGQRTSFSSSLSQTQDLSVYRHRSSLLHKKTGMREEMSLGRQEAFEIFKRDHADSVTIED 576

  Fly   619 QRRLCEDIISSQRRLIEEGNVDLPDELRELYG--------LYQQEIHAGV----VTPSTSN-YER 670
            .:::.:...|..:.|.|..|     |.|...|        .:.|::..|:    ..|||.: .|:
  Rat   577 NKQVLKQRFSEAKALGESIN-----EARSKIGQLKEAISQRHLQQVALGIAESMAPPSTPDPQEQ 636

  Fly   671 KL 672
            ||
  Rat   637 KL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:277568	111/360 (31%)
		Kinesin	41..371	CDD:278646	111/354 (31%)
Kif6	XP_006244542.1	KISc_KIF9_like	5..343	CDD:276826	111/362 (31%)
		Kinesin	28..345	CDD:278646	105/341 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810