| Sequence 1: | NP_996208.1 | Gene: | Kif19A / 41717 | FlyBaseID: | FBgn0038205 | Length: | 750 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001804.2 | Gene: | CENPE / 1062 | HGNCID: | 1856 | Length: | 2701 | Species: | Homo sapiens |
| Alignment Length: | 778 | Identity: | 206/778 - (26%) |
|---|---|---|---|
| Similarity: | 326/778 - (41%) | Gaps: | 205/778 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 31 AQEERLVVAVRVRPSMEATERCIEVI-----SGGSLLYD-DGGKSRPRQYSYDHVFRENDSQEQV 89
Fly 90 YKTTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTASCDSTDVSSQDI 154
Fly 155 GLMVRAIEDIFSHIESAEAYSCRVSISYLEIYNELIRDLL---NPGGPLELREDHRGQRITVAGL 216
Fly 217 SEITTSSRKEVVSLLLKGNKARTMEPTAANQTSSRSHALLSIMVQAR---TPL----GTKQGRLF 274
Fly 275 LTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGLSGG--ARYVNYRDSKLTRLLKEALS 337
Fly 338 GRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVSELRDE 402
Fly 403 VSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTE---LRYLREQIV- 463
Fly 464 ---LTFKQQMKLRRKL--------------------------LEAESHLLGLELDAERQHMIISH 499
Fly 500 WQGRIGKLYDAMGDDDIESEGSVALK-----NAWGELAAIEKE----TRRYKEIR-ERTEHELEQ 554
Fly 555 CRQKGVKLEDELPERISSDEERELLALLCRVHELEADKVSLQAERLARQAELRRRDL-------- 611
Fly 612 QLLR-AERQRRLCEDIISSQR---------------------------------------RLIEE 636
Fly 637 GNVDLPDELREL----------YGLYQQEIHA----------------GVVTPSTSNYERKLP 673 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Kif19A | NP_996208.1 | Motor_domain | 35..371 | CDD:277568 | 130/353 (37%) |
| Kinesin | 41..371 | CDD:278646 | 128/347 (37%) | ||
| CENPE | NP_001804.2 | KISc | 6..336 | CDD:214526 | 132/364 (36%) |
| KISc_CENP_E | 6..329 | CDD:276825 | 130/357 (36%) | ||
| SbcC | 345..915 | CDD:223496 | 70/395 (18%) | ||
| Mplasa_alph_rch | 660..1366 | CDD:275316 | 9/50 (18%) | ||
| NUDE_C | 828..>911 | CDD:282704 | |||
| Mplasa_alph_rch | 1151..1951 | CDD:275316 | |||
| Smc | 1676..2482 | CDD:224117 | |||
| Kinetochore-binding domain | 2126..2476 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2355..2376 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2508..2533 | ||||
| Globular autoinhibitory domain. /evidence=ECO:0000250 | 2510..2698 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2588..2701 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0242 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||